BACKGROUND: Burnout is a growing problem in medical education, and is usually characterised by three dimensions: emotional exhaustion, cynicism, and reduced professional efficacy. Currently, the majority of burnout studies have been conducted in western high-income countries, overshadowing findings from low- and middle-income countries. Our objecti...
KCNQ1/Kv7, a low-voltage-gated K+ channel, regulates cardiac rhythm and glucose homeostasis. While KCNQ1 mutations are associated with long-QT syndrome and type2 diabetes, its function in human pancreatic cells remains controversial. We identified a homozygous KCNQ1 mutation (R397W) in an individual with permanent neonatal diabetes melitus (PNDM) w...
Race at sea: revisiting Alexander Falconbridge’s Account of the Slave Trade on the Coast of Africa (1788)Falconbridge’s book, Account of the Slave Trade on the Coast of Africa, was published in 1788 after Falconbridge met with Thomas Clarkson and left the slave trade. The account became influential in the abolitionist milieux in England. Falconbrid...
L’endométriose est une maladie gynécologique hormonodépendante chronique touchant près de 1 femme sur 10. Pourtant, jusqu’à récemment, elle demeurait relativement mal connue du grand public et des professionnels de santé avec une errance médicale de 7 ans en moyenne afin de poser un diagnostic. Il s’agit d’une pathologie qui peut être réellement in...
Published in Frontiers in Pediatrics
Introduction Preoperative three-dimensional (3D) reconstruction using sectional imaging is increasingly used in challenging pediatric cases to aid in surgical planning. Many case series have described various teams' experiences, discussing feasibility and realism, while emphasizing the technological potential for children. Nonetheless, general know...
Published in Medical teacher
Making a career choice is a multifaceted process and support for medical students on career choice is pivotal. Not all medical schools have programs or guidelines to support having meaningful conversations with medical students. However, medical students have questions and are seeking answers. This article presents twelve tips for having meaningful...
Objectives: Provide an overview of the methods used to estimate the cost of sports-related injury published to date, and to highlight considerations and opportunities for future research. Design: Scoping review. Methods: Scopus, MEDLINE and CINHAL were searched from 1st January 2000 to 1st January 2023. Studies were screened by two independent revi...
Published in Computers in biology and medicine
Artificial intelligence (AI) has revolutionized many fields, and its potential in healthcare has been increasingly recognized. Based on diverse data sources such as imaging, laboratory tests, medical records, and electrophysiological data, diagnostic AI has witnessed rapid development in recent years. A comprehensive understanding of the developmen...
Primary care is at the forefront of healthcare delivery. It is the site of disease prevention and health management and serves as the bridge between communities and the health care system As ethnographers of primary care, in this article we discuss what is gained by situating anthropological inquiry within primary care. We articulate how anthropolo...
Published in Clinical therapeutics
The bad bitter taste of some medicines is a barrier to overcoming noncompliance with medication use, especially life-saving drugs given to children and the elderly. Here, we evaluated a new class of bitter blockers (thiazolidinediones, TZDs). In this study, 2 TZDs were tested, rosiglitazone (ROSI) and a simpler form of TZD, using a high-potency swe...
