Published in Seminars in respiratory and critical care medicine
Among the viruses possibly responsible for hospital-acquired and ventilator-associated pneumonia, herpes simplex virus (HSV) is probably the most often involved: HSV reactivation is frequent in intensive care unit patients, and lung parenchymal infection (HSV bronchopneumonitis) has been well described, either using cytological signs of parenchymal...
Barotrauma is damage to body tissue secondary to pressure difference in closed cavities within the body. Since positive pressure ventilation is not physiologic, it can lead to complications such as barotrauma. Pulmonary barotrauma is the presence of extra alveolar air in places where it is not present under normal circumstances. Excess alveolar air...
Published in Journal of Korean Medical Science
Published in Journal of Otolaryngology - Head & Neck Surgery
BackgroundDuring the early part of the COVID-19 pandemic, the Canadian Society of Otolaryngology - Head & Neck Surgery (CSO-HNS) task force published recommendations on performance of tracheotomy. Since then, our understanding of the virus has evolved with ongoing intensive research efforts. New literature has helped us better understand various as...
Published in International Journal of Emergency Medicine
BackgroundPatients with acute respiratory failure, impaired consciousness, and impaired airway reflexes will require invasive mechanical ventilation. Monitoring of such patients is important. The use of ventilator scalars and loops help in monitoring, diagnosing the abnormality, and treating the patients effectively. We report a rare cause one shou...
Published in Intensive Care Medicine Experimental
BackgroundInduced hypernatremia and hyperosmolarity is protective in animal models of lung injury. We hypothesized that increasing and maintaining plasma sodium between 145 and 150 mmol/l in patients with moderate-to-severe ARDS would be safe and will reduce lung injury. This was a prospective randomized feasibility study in moderate-to-severe ARDS...
Published in Journal of Tropical Pediatrics
Objectives To describe the intensive care needs and outcome of Multisystem Inflammatory Syndrome in Children (MIS-C). Methodology This retrospective study was conducted in the Pediatric Emergency and Intensive Care Units and COVID-19 hospital of a tertiary care teaching and referral hospital in North India over a period of 5 months (September 2020-...
Published in Medical Journal of the Islamic Republic of Iran
Background: High tidal volume leads to inflammation, and low tidal volume leads to atelectasia and hypoxemia. This study was conducted to compare the effect of 6 mL/kg with positive end-expiratory pressure (PEEP) and 8 mL/kg without PEEP on pulmonary shunt and dead space volume. Methods: This clinical trial was done on 36 patients aged 20 to 65 yea...
Published in Respiratory Medicine
Published in Reference Module in Biomedical Sciences
Ventilatory support, while life saving, can also cause or aggravate lung injury through several mechanisms which are encompassed within ventilator-associated lung injury (VALI). The important realizationin the acute respiratory distress syndrome that the “baby” lung resided in non-dependent areas led to the conceptualization of “lung rest” to reduc...
