Viguerie, Alex Lorenzo, Guillermo Auricchio, Ferdinando Baroli, Davide Hughes, Thomas J R Patton, Alessia Reali, Alessandro Yankeelov, Thomas E Veneziani, Alessandro
Published in
Applied mathematics letters
We present an early version of a Susceptible-Exposed-Infected-Recovered-Deceased (SEIRD) mathematical model based on partial differential equations coupled with a heterogeneous diffusion model. The model describes the spatio-temporal spread of the COVID-19 pandemic, and aims to capture dynamics also based on human habits and geographical features. ...
Grespan, Eleonora Giorgino, Toni Natali, Andrea Ferrannini, Ele Mari, Andrea
Published in
Metabolism: clinical and experimental
The reduced action of incretin hormones in type 2 diabetes (T2D) is mainly attributed to GIP insensitivity, but efficacy estimates of GIP and GLP-1 differ among studies, and the negligible effects of pharmacological GIP doses remain unexplained. We aimed to characterize incretin action in vivo in subjects with normal glucose tolerance (NGT) or T2D ...
Bonin, Carla Rezende Barbosa Fernandes, Guilherme Côrtes de Menezes Martins, Reinaldo Camacho, Luiz Antonio Bastos Teixeira-Carvalho, Andréa da Mota, Licia Maria Henrique de Lima, Sheila Maria Barbosa Campi-Azevedo, Ana Carolina Martins-Filho, Olindo Assis dos Santos, Rodrigo Weber
...
Published in
BMC Bioinformatics
BackgroundAn effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among othe...
Parra-Rojas, César Fürtig, Boris Schwalbe, Harald Hernandez-Vargas, Esteban A
Published in
Journal of theoretical biology
Riboswitches are cis-acting regulatory mRNA elements in bacteria, that modulate the expression of their associated genes in response to a cognate metabolite, operating either on the level of translation or transcription. Transcriptional riboswitches have to fold into functional structures as they are being synthesized and, only if transcription rat...
Motta-Ribeiro, Gabriel C Vidal Melo, Marcos F Jandre, Frederico C
Published in
Journal of clinical monitoring and computing
To evaluate a compact and easily interpretable 4-parameter model describing the shape of the volumetric capnogram, and the resulting estimates of anatomical dead space (VDAW) and Phase III (alveolar plateau) slope (SIII). Data from of 8 mildly-endotoxemic pre-acute respiratory distress syndrome sheep were fitted to the proposed 4-parameter model (4...
Din, Rahim Ud Seadawy, Aly R Shah, Kamal Ullah, Aman Baleanu, Dumitru
Published in
Results in physics
The theme of this paper focuses on the mathematical modeling and transmission mechanism of the new Coronavirus shortly noted as (COVID-19), endangering the lives of people and causing a great menace to the world recently. We used a new type epidemic model composed on four compartments that is susceptible, exposed, infected and recovered (SEIR), whi...
Domenech de Cellès, Matthieu Campbell, Helen Borrow, Ray Taha, Muhamed-Kheir Opatowski, Lulla
Published in
BMC Medicine
BackgroundThe recent emergence of strains belonging to the meningococcal serogroup W (MenW) sequence type-11 clonal complex and descending from the South American sub-lineage (MenW:cc11/SA) has caused significant shifts in the epidemiology of meningococcal disease worldwide. Although MenW:cc11/SA is deemed highly transmissible and invasive, its epi...
Neves, Armando G M Guerrero, Gustavo
Published in
Physica D. Nonlinear phenomena
The presence of a large number of infected individuals with few or no symptoms is an important epidemiological difficulty and the main mathematical feature of COVID-19. The A-SIR model, i.e. a SIR (Susceptible-Infected-Removed) model with a compartment for infected individuals with no symptoms or few symptoms was proposed by Gaeta (2020). In this p...
Molenberghs, Geert; 56633; Buyse, Marc; Abrams, Steven; Hens, Niel; Beutels, Philippe; Faes, Christel; Verbeke, Geert; Van Damme, Pierre; Goossens, Herman; Neyens, Thomas;
...
Starting from historic reflections, the current SARS-CoV-2 induced COVID-19 pandemic is examined from various perspectives, in terms of what it implies for the implementation of non-pharmaceutical interventions, the modeling and monitoring of the epidemic, the development of early-warning systems, the study of mortality, prevalence estimation, diag...
Camargos, Cristiane Vieira Moraes, Vitória Demétrio de Oliveira, Liliane Maciel Guidini, Carla Zanella Ribeiro, Eloízio Júlio Santos, Líbia Diniz
Published in
Applied biochemistry and biotechnology
Substantial progress has been made in ethanol fermentation technology under high gravity (HG) and very high gravity (VHG), which offer environmental and economic benefits. HG and VHG processes increase the productivity of ethanol, reduce distillation costs, and enable higher yields. The aim of the present study was to evaluate the use of sugarcane ...
