The present article introduces an automated procedure to construct geometrical Representative Volume Elements (RVE) of open-foam cellular materials from com- puterized tomography (CT) images, with the final aim of generating meshable geometries usable in the Finite Element Method (FEM) used in order to analyse their mechanical behaviour. The method...
Published in The spine journal : official journal of the North American Spine Society
Intraoperative detection of a pedicle wall breach implicitly reduces surgical risk, but the reliability of intraoperative neuromonitoring has been contested. Hydroxyapatite (HA) has been promulgated to increase pedicle screw resistance and negatively influence the accuracy of electromyography. The primary purpose of this experiment is to evaluate t...
Published in International Journal of Pharmaceutics: X
• The impact of particle size on the re-compactibility differs per excipient type. • Re-compactibility is classified and quantified for different excipients. • Rough surfaces and a high degree of fragmentation are beneficial for re-compaction. • The particle size of anhydrous lactose hardly affects the re-compactibility.
Published in Biosafety and Health
Since its outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has strongly influenced the life of the general public around the world. Based on its fast spread and high mortality, there is a need for novel therapeutic treatments to overcome this global health crisis. While medicinal chemistry is focused on the development of ...
Cette thèse s’inscrit dans le cadre du développement de matériaux innovants pour des applications multifonctionnelles (en micro/nanotechnologies, en métallurgie, …). En effet, les cahiers des charges « Matériaux » de ces développements exigent de plus en plus de combiner diverses propriétés (mécaniques, électriques, diélectriques, …) qui sont parfo...
Published in Biosafety and health
Coronavirus disease 2019 (COVID-19) has rapidly swept around the globe since its emergence near 2020. However, people have failed to fully understand its origin or mutation. Defined as an international biosafety incident, COVID-19 has again encouraged worldwide attention to reconsider the importance of biosafety due to the adverse impact on persona...
La découverte de matériaux repose principalement sur l'analyse de données expérimentales obtenues par variation des paramètres des procédés de fabrication et en observant les propriétés des matériaux ainsi créés. L'Intelligence Artificielle (IA) a été appliquée à ce domaine, proposant des modèles pouvant prédire les performances des nouveaux matéri...
Particles stabilize fluid interfaces. In particular, oil/water Pickering emulsions undergo limited coalescence, yielding droplets of smaller size as the amount of particles is increased. Herein, we studied the effect of hydrophobic nanoparticles (
Published in Journal of pharmaceutical sciences
Growth of mammalian cells in the production of biotherapeutics often require the benefits of chemically defined media (CDM). Storage, handling and stability advantages of CDM powders govern the preponderance of their use across the industry. Physico-chemical property lot-to-lot variation of these multicomponent powders, however, continues to be a c...
Additive manufacturing (AM), also known as 3D-printing, has made it possible to produce components made of bulk metallic glass (BMG) which have remarkable properties compared to parts made of conventional alloys. A metallic glass is a metastable noncrystalline alloy that form if a melt is quenched with a sufficient cooling rate. Research on systems...
