Lebeau, Diane Leroy, Nathalie Doizi, Denis Wu, Ting-Di Guerquin-Kern, Jean-Luc Perrin, Laura Ortega, Richard VOISEUX, Claire Fournier, Jean-Baptiste Potin, Philippe
...
129I is one of the main radioisotopes of iodine derived from the nuclear fuel cycle that can be found sustainably in the environment due to its long half-life. In coastal marine environment, brown macroalgae, such laminariales (or kelps), are known to naturally feature highest rates of iodine accumulation, and to be an important source of biogenic ...
Yüce, Meral Sert, Fatma Torabfam, Milad Parlar, Ayhan Gürel, Büşra Çakır, Nilüfer Dağlıkoca, Duygu E Khan, Mansoor A Çapan, Yılmaz
Published in
Analytica chimica acta
The similarity between originator and biosimilar monoclonal antibody candidates are rigorously assessed based on primary, secondary, tertiary, quaternary structures, and biological functions. Minor differences in such parameters may alter target-binding, potency, efficacy, or half-life of the molecule. The charge heterogeneity analysis is a prerequ...
Sun, Jun Mu, Yaoyao Liu, Tengmei Jing, Hui Obadi, Mohammed Yang, Yanjun Dong, Shijian Xu, Bin
Published in
Food chemistry
An important relationship exists between the changes in glycation sites and structure of proteins. A combination of liquid chromatography and tandem mass spectrometry was used to identify the glycation information from ovalbumin (OVA) after dextran (Dex) conjugation under water heating (WH) or microwave heating (MH) conditions. After Dex conjugatio...
Brandt, Sophie C. Brognaro, Hévila Ali, Arslan Ellinger, Bernhard Maibach, Katharina Rühl, Martin Wrenger, Carsten Schlüter, Hartmut Schäfer, Wilhelm Betzel, Christian
...
Published in
Biotechnology for Biofuels
BackgroundThe transition to a biobased economy involving the depolymerization and fermentation of renewable agro-industrial sources is a challenge that can only be met by achieving the efficient hydrolysis of biomass to monosaccharides. In nature, lignocellulosic biomass is mainly decomposed by fungi. We recently identified six efficient cellulose ...
Yang, Lele Xue, Yan Wei, Jinchao Dai, Qi Li, Peng
Published in
Chinese Medicine
BackgroundJinqi Jiangtang (JQJT) has been widely used in clinical practice to prevent and treat type 2 diabetes. However, little research has been done to identify and classify its quality markers (Q-markers) associated with anti-diabetes bioactivity. In this study, a strategy combining mass spectrometry-based untargeted metabolomics with backpropa...
Ogilvie, Olivia Roberts, Sarah Sutton, Kevin Larsen, Nigel Gerrard, Juliet Domigan, Laura
Published in
Food chemistry
Microbial transglutaminase (mTG) catalyses the formation of protein crosslinks, deamidating glutamine in a side-reaction. Gluten deamidation by human tissue transglutaminase is critical to activate celiac disease pathogenesis making the addition of mTG to wheat-based products controversial. The ability of mTG (0-2000 U.kg-1) to alter gluten's struc...
Bruno, C Veyrat-Durebex, C Lumbu Lukuntonda, C H Andres, C R Moreau, Nicolas Bendavid, C Homedan, C Labarthe, F Tardieu, M Bigot, A
...
INTRODUCTION: Amino acid (AA) analysis in plasma is essential for diagnosis and monitoring of inborn errors of metabolism (IEM). The efficacy of patient management is governed by the rapidity of AA profile availability, along with the robustness of the method. French quality guidelines and progress made in analytical techniques have led biologists ...
Kiritani, Sho Yoshimura, Kentaro Arita, Junichi Kokudo, Takashi Hakoda, Hiroyuki Tanimoto, Meguri Ishizawa, Takeaki Akamatsu, Nobuhisa Kaneko, Junichi Takeda, Sen
...
Published in
BMC Cancer
BackgroundProbe electrospray ionization-mass spectrometry (PESI-MS) can rapidly visualize mass spectra of small, surgically obtained tissue samples, and is a promising novel diagnostic tool when combined with machine learning which discriminates malignant spectrum patterns from others. The present study was performed to evaluate the utility of this...
Kalaitzidou, Maria P. Nannou, Christina I. Lambropoulou, Dimitra A. Papageorgiou, Konstantinos V. Theodoridis, Alexandros M. Economou, Vangelis K. Giantsis, Ioannis A. Angelidis, Panagiotis G. Kritas, Spyridon K. Petridou, Evanthia J.
...
Published in
Journal of Biological Research-Thessaloniki
BackgroundMicrocystins are emerging marine biotoxins, produced by potentially toxic cyanobacteria. Their presence has been reported in aquatic animals in Greek freshwater, while data are few in marine environments. Since the climate change induces eutrophication and harmful algal blooms in coastal marine ecosystems affecting the public health, furt...
Filatova, Daria Jones, Martin R. Haley, John A. Núñez, Oscar Farré, Marinella Janssen, Elisabeth M.-L.
Published in
Environmental Sciences Europe
BackgroundBloom-forming cyanobacteria occur globally in aquatic environments. They produce diverse bioactive metabolites, some of which are known to be toxic. The most studied cyanobacterial toxins are microcystins, anatoxin, and cylindrospermopsin, yet more than 2000 bioactive metabolites have been identified to date. Data on the occurrence of cya...