Hu, Yongjun Gruber, Kenneth A Smith, David E
Published in
Journal of cachexia, sarcopenia and muscle
Cachexia is a debilitating, life-threatening condition whose pathology includes reduced food intake accompanied by hypermetabolism, leading to a catabolic state. The hypothalamic melanocortin system is a critical regulator of metabolic rate with effects being mediated through the melanocortin-4 receptor (MC4R). MC4R activation is also critical to t...
Deprá, Mariany C Dias, Rosangela R Severo, Ihana A de Menezes, Cristiano R Zepka, Leila Q Jacob-Lopes, Eduardo
Published in
Bioresource technology
This research evaluated the carbon dioxide capture and use by Scenedesmus obliquus in a photobioreactor under different CO2 loads. Performance indicators, carbon and energy balances, sustainability indicators, and carbon credits on the photobioreactor were assessed. The results expressed that the CO2 loads of 384.9 kg/m3/d (15% CO2) provide the bes...
Lei, Hao-Jun Yang, Bin Ye, Pu Yang, Yuan-Yuan Zhao, Jian-Liang Liu, You-Sheng Xie, Lingtian Ying, Guang-Guo
Published in
The Science of the total environment
Benzodiazepines (BZDs) are one of the most widely prescribed psychoactive drugs, however their persistence in the receiving environment has raised great concerns about their potential ecological risks. Here we investigated the occurrence, fate and mass loading of 17 BZDs and their 3 transformation products in 11 wastewater treatment plants (WWTPs) ...
Papež, Jan Rüde, Ulrich Vohralík, Martin Wohlmuth, Barbara
We derive guaranteed, fully computable, constant-free, and sharp upper and lower a posteriori estimates on the algebraic, total, and discretization errors of finite element approximations of the Poisson equation obtained by an arbitrary iterative solver. The estimators are computed locally over patches of mesh elements around vertices and are based...
Duan, Yanqing Zhou, Aijuan Yue, Xiuping Zhang, Zhichun Gao, Yanjuan Luo, Yanhong Zhang, Xiao
Published in
Frontiers of Environmental Science & Engineering
To address the availability of carbon sources for denitrification, the accelerated hydrolysis of the most abundant but low-availability fraction of particulate organic matter (POM) was investigated. Mesh sieves with different pore sizes were used as primary pretreatment at the start-up-stage of the biological process to separate some POM from the l...
Khan, Nawaz Chowdhary, Pankaj Ahmad, Anees Shekher Giri, Balendu Chaturvedi, Preeti
Published in
Bioresource technology
This work studied the hydrothermal liquefaction of rice husk (RH) and cow dung (CD) for the production of biochar from RH and CD and use of that biochar for the removal of dye from textile industry effluent. These biomasses were subjected to fast pyrolysis (500 °C), which yielded biochar (22.8 and 29.8%) and bio-oil (60.4 and 57.3%) from RH and CD,...
Roosendaal, Jeroen Rosing, Hilde Lucas, Luc Gebretensae, Abadi Huitema, Alwin D R van Dongen, Marloes G Beijnen, Jos H Oganesian, Aram
Published in
Investigational new drugs
Purpose The objective of this mass balance trial was to determine the excretory pathways and metabolic profile of the novel anticancer agent guadecitabine in humans after administration of a 14C-radiolabeled dose of guadecitabine. Experimental design Included patients received at least one cycle of 45 mg/m2 guadecitabine subcutaneously as once-dail...
Macêdo Aranha, Rayanne A. Magalhães, Vivian M. P. Mendes, Gabriela R. Soares, Lélia C. Muselli Barbosa, Alexandre A. O. Nascimento, Claudio M. G. R. Vianna, Marilda Chiavone-Filho, Osvaldo
Published in
Water, Air, & Soil Pollution
Creosote is a multicomponent oil classified as a dense non-aqueous phase liquid (DNAPL) produced from coal tar distillation. The concept of phase distribution is critical in decision-making to remediate contaminated sites. The creosote mass transfer between sorbed, aqueous, vapor, and DNAPL phases is controlled by physicochemical characteristics, g...
Arencibia-Albite, Francisco
Published in
Heliyon
Applied Mathematics; Metabolism; Physiology; Biological Sciences; Pathophysiology; Health Sciences; Body weight; Energy Balance; Low-Fat Diet; Low-Carbohydrate Diet; Mass Balance
Liao, Mingxiang Watkins, Simon Nash, Eileen Isaacson, Jeff Etter, Jeff Beltman, Jeri Fan, Rong Shen, Li Mutlib, Abdul Kemeny, Vendel
...
Published in
Investigational new drugs
Rucaparib, a poly(ADP-ribose) polymerase inhibitor, is licensed for use in recurrent ovarian, fallopian tube, or primary peritoneal cancer. We characterized the absorption, distribution, metabolism, and elimination of rucaparib in 6 patients with advanced solid tumors following a single oral dose of [14C]-rucaparib 600 mg (≈140 μCi). Total radioact...
