The Dutch railway system is subject to maintenance, which is carried out by a group of rail contractors who need parking space to park and prepare trains in between projects. The objective of this study is to minimise the total costs as a result of the distance travelled by maintenance trains and the preservation of the included parking locations i...
Published in Data-Enabled Discovery and Applications
The concept of equipment maintenance is older than the industrial revolution. The mode, medium, and timing of maintenance during equipment life cycle have evolved from reactive maintenance to predictive maintenance to prescriptive maintenance. Prescriptive maintenance, which incorporates the Internet of Things, digitization, and artificial intellig...
The increased use of plant ingredients in aquafeeds over the last decades, as replacement for fish meal, has led to rising levels of undesired non-starch polysaccharides (NSP) and phytate. Both NSP and phytate degrading enzymes and probiotics have been widely studied. They can be used as a tool to deal with increasing levels of NSP and phytate in a...
Gully pots actively trap sediments transported by urban runoff to prevent in-pipe blockages and surface flooding. However, due to poor maintenance (resulting in sediment build-up) and increasingly extreme wet weather events, the scour of previously-deposited sediments from gully pots is identified as a potential contributor to EU Water Framework Di...
Published in Case Reports in Oncology
A standard chemotherapy regimen for advanced thymic carcinoma has not yet been established. We treated 2 cases of thymic carcinoma with carboplatin plus nanoparticle albumin-bound (nab)-paclitaxel, and nab-paclitaxel maintenance therapy. The first case was a 68-year-old female, admitted for dyspnea and left shoulder pain. Chest computed tomography ...
Published in Journal of Crohn's & colitis
Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis. We present primary completion analysis from RIVETING, an ongoing, double-blind, randomized, parallel-group trial evaluating efficacy and safety of tofacitinib dose reduction to 5 mg twice daily [BID] versus remaining on 10 mg BID in patients in st...
Published in Data-Enabled Discovery and Applications
Journey by aircraft is the only option for long-distance transportation and also one of the frequently used modes of transportation of passengers. As a result, safety of passengers and efficiency of the aircraft depend on maintaining efficient running conditions. Although many safety standards are followed in the design of the aircraft, and thus th...
Published in Acta tropica
Balantioides coli is a known ciliated zoonotic protozoan that mainly causes diarrhea in humans and pigs. An efficient and reliable culture system for this parasite remains unavailable until now. In this study, a modified Dulbecco's modified eagle medium (DMEM) with pH 7.0-7.5, containing 5 mg/mL starch and 20% new calf serum, was optimized for prop...
Published in The journals of gerontology. Series B, Psychological sciences and social sciences
Goal orientation tends to shift from predominantly striving for gains to maintenance and loss avoidance across adulthood. A dominant hypothesis states that age-related increases in losses drive the motivational shift. The present study tests this hypothesis and an alternative, namely that perceived accumulation of resources/assets and discrepancy b...
Published in Schizophrenia research
There is a long-lasting debate regarding the long-term antipsychotic treatment of schizophrenia. The most frequently advocated strategy is continued antipsychotic maintenance treatment (i.e., continuous treatment with a constant dose of antipsychotic medication after symptom remission). Yet, because of the potential side effects of continued antips...
