Published in Expert review of vaccines
Vaccination is an effective strategy to combat invasive meningococcal disease (IMD). Vaccines against the major disease-causing meningococcal serogroups are available; however, development of vaccines against serogroup B faced particular challenges, including the inability to target traditional meningococcal antigens (i.e. polysaccharide capsule) a...
Published in The Journal of infection
Serogroup B meningococci (MenB) remain a prominent cause of invasive meningococcal disease (IMD). The protein-based multicomponent 4CMenB and the bivalent MenB-FHbp are the only currently available vaccines against MenB-caused IMD. Efficacy studies are not possible, due to the low incidence of IMD. Therefore, the vaccines' immunogenicity has been e...
Published in Expert review of vaccines
The successful development of two broadly protective vaccines targeting Neisseria meningitidis serogroup B (MenB); 4CMenB and rLP2086, is the most significant recent advance in meningococcal disease prevention. Areas covered: Here we review the principles underlying the development of each vaccine and the novel methods used to estimate vaccine cove...
Published in The Journal of rheumatology
The level of agreement between 2 commonly used fracture risk assessment tools was not as high in the patients with fragility fractures as it was in general community-based samples. Our results suggest discordance is found in less-typical patients with OP who need more consistency in messaging and direction. Users of these fracture risk tools should...
Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cientiico e Tecnologico) CNPq
Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cientiico e Tecnologico) CNPq
Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cientiico e Tecnologico) CNPq
Soil vapour migration into buildings, and subsequent inhalation, are often the main exposure pathway to humans at sites contaminated with Volatile Organic Compounds (VOCs). For such sites, the quantification of pollutant concentrations in the indoor air is essential while assessing risks for the human health. Modeling is often necessary, for exampl...
Published in General hospital psychiatry
To develop a user-friendly scale that measures traumatic stress responses in injured children. Though injured youth are at high risk for traumatic stress reactions and negative sequelae, there are limited options available for assessing risk, particularly in acute settings. Participants were children and adolescents (ages 6-18) hospitalized with bu...
Bathymetry on continental hydrographic networks is up to now limited to small areas. This hampers exhaustive hydrological or ecological studies on hydrographic networks at management scales. To enlarge rivers bathymetry surveys, bathymetric, i.e. green LiDAR appears as an interesting tool. But if this technique has been widely used for coastal surv...
