Published in BMC Cancer
BackgroundRecently, the incidence of gastroesophageal junction (GEJ) cancer has been increasing in Eastern countries. Mediastinal lymph node (MLN) metastasis rates among patients with GEJ cancer are reported to be 5–25%. However, survival benefits associated with MLN dissection in GEJ cancer has been a controversial issue, especially in Eastern cou...
Published in BMC Cancer
BackgroundChronic lymphocytic leukemia is a malignancy with good prognosis. However, the incidence of secondary tumors increases every year after the diagnosis of chronic lymphotcytic leukemia. One of the induced secondary tumors is prostate cancer. For high-risk prostate cancer in particular, the standard therapy is radical prostatectomy and exten...
Published in BMC Cancer
BackgroundAn important parameter for survival in patients with esophageal carcinoma is lymph node status. The distribution of lymph node metastases depends on tumor characteristics such as tumor location, histology, invasion depth, and on neoadjuvant treatment. The exact distribution is unknown. Neoadjuvant treatment and surgical strategy depends o...
Published in best practice onkologie
Während sich in den Industrienationen die Inzidenz des Zervixkarzinoms seit Jahren rückläufig zeigt, ist die durch eine persistierende Infektion mit HPV (humanen Papillomviren) ausgelöste Erkrankung in Schwellen- und Entwicklungsländern nach wie vor sehr häufig. Durch ein effektives Screening mittels Abstrichzytologie gelingt meist die Diagnose ein...
Published in Der Onkologe
HintergrundDer Lymphknotenbefall der Leiste ist der zentrale Prognosefaktor für Rezidivrisiko und Überleben bei Patientinnen mit Vulva- und Vaginalkarzinom. Im letzten Jahrzehnt hat die Sentinellymphonodektomie (SNB, Wächterlymphknotenbiopsie) insbesondere beim Vulvakarzinom Einzug in die klinische Routine erhalten.ZielDie aktuelle Datenlage und Em...
Published in Journal of Cancer Research and Clinical Oncology
PurposeThe lack of prognostic data impedes implementation of optimal therapy for cervical cancer. For instance, recommended therapy for FIGO IIB cervical cancer is radical hysterectomy or radiochemotherapy. To enlighten different therapeutic approaches, we investigated the benefit of individual therapies or combination thereof in patients with or w...
Published in World Journal of Surgical Oncology
BackgroundTo determine the optimal timing of duodenal transection in patients undergoing laparoscopic-assisted total gastrectomy (LATG) in combination with laparoscopic spleen-preserving splenic hilar lymphadenectomy (LSPL) for advanced proximal gastric cancer (APGC).MethodsOne hundred twenty-seven patients with APGC who received LATG with duodenal...
Published in Journal of Cancer Research and Clinical Oncology
PurposeThe European Association of Urology (EAU) guidelines for penile cancer (PC) are exclusively based on retrospective studies and have low grades of recommendation. The aim of this study was to assess the adherence to guidelines by investigating the management strategies for primary tumours and inguinal lymph nodes.MethodsWe retrospectively rev...
Published in Journal of Gastrointestinal Cancer
BackgroundEarly gastric cancer (EGC) is more common nowadays and is related a to low percentage of lymph node metastasis. For this reason, there is enormous interest to implicate minimally invasive approaches. Recently, special efforts have been made towards a potential intraoperative (real-time) lymph node metastasis (LNM) assessment, as nodal dis...
Published in Journal of Gastrointestinal Surgery
BackgroundMeckel’s diverticulum (MD) is an anomaly of the small intestine from which malignancy may arise. Among MD neoplasms, neuroendocrine tumors (NETs) are considered the most common. However, their metastatic potential and optimal surgical therapy remain ill-defined.MethodsIn a retrospective analysis of the National Cancer Database (2004–2015)...
