Venkat, Puja S Smick, Alexandra H Salani, Ritu
Purpose of reviewTo review the recent updates in the management of cervical cancer across all stages of the disease.Recent findingsAfter decades of minor advances, the landscape in cervical cancer is now rapidly changing. Recent studies have reported across the cervical cancer spectrum and on different therapeutic modalities. First, less radical su...
Pina Martínez, Víctor
[ES] NzuriAqua es un dispositivo innovador diseñado para depurar y desalinizar agua contaminada de mares y ríos mediante los procesos físicos de evaporación y condensación de fluidos. Este dispositivo está concebido para ser fabricado in situ en localidades con necesidades urgentes de agua potable, utilizando materiales locales como arcilla y cera ...
Meehan, John
Dilute povidone-iodine (polyvinylpyrrolidone iodine [PVP-I]) irrigation in spine surgery and total joint arthroplasty has seen a rapid and substantial increase in its use during the past decade. Yet, most surgeons do not know the chemistry and biochemistry that explain its efficacy in preventing infections. PVP-I forms a complex with molecular iodi...
Lucas, Calixto-Hope G Al-Adli, Nadeem N Young, Jacob S Gupta, Rohit Morshed, Ramin A Wu, Jasper Ravindranathan, Ajay Shai, Anny Oberheim Bush, Nancy Ann Taylor, Jennie W
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BackgroundDespite recent advances in the biology of IDH-wildtype glioblastoma, it remains a devastating disease with median survival of less than 2 years. However, the molecular underpinnings of the heterogeneous response to the current standard-of-care treatment regimen consisting of maximal safe resection, adjuvant radiation, and chemotherapy wit...
Bryce, Alan Agarwal, Neeraj Beltran, Himisha Hussain, Maha Sartor, Oliver Shore, Neal Antonarakis, Emmanuel Armstrong, Andrew Calais, Jeremie Carducci, Michael
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Current US clinical practice guidelines for advanced prostate cancer management contain recommendations based on high-level evidence from randomized controlled trials; however, these guidelines do not address the nuanced clinical questions that are unanswered by prospective trials but nonetheless encountered in day-to-day practice. To address these...
Sesanto, Christine Lawrence, Jessica Holkham, Jocelyn Serra, Juan Bavcar, Spela Parys, Magdalena
A 9.5-year-old male neutered domestic short-haired cat received two courses of postoperative, definitive-intent conformal radiation therapy (RT) for recurrent laryngeal adenocarcinoma (LACA). Adjuvant RT was prescribed (16 × 3.0 Gy, total 48 Gy) following incomplete resection. Following tumor recurrence and subsequent incomplete resection 31.5 mont...
Oshima, Sonoko Yao, Jingwen Bobholz, Samuel Nagaraj, Raksha Raymond, Catalina Teraishi, Ashley Guenther, Anna-Marie Kim, Asher Sanvito, Francesco Cho, Nicholas S
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Aim: A radio-pathomic machine learning (ML) model has been developed to estimate tumor cell density, cytoplasm density (Cyt) and extracellular fluid density (ECF) from multimodal MR images and autopsy pathology. In this multicenter study, we implemented this model to test its ability to predict survival in patients with recurrent glioblastoma (rGBM...
McFaline-Figueroa, J Sun, Lu Youssef, Gilbert Huang, Raymond Li, Gang Kim, Jiyoon Lee, Eudocia Nayak, Lakshmi Chukwueke, Ugonma Beroukhim, Rameen
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Glioblastoma is immunologically cold and resistant to single-agent immune-checkpoint inhibitors (ICI). Our previous study of neoadjuvant pembrolizumab in surgically-accessible recurrent glioblastoma identified a molecular signature of response to ICI and suggested that neoadjuvant pembrolizumab may improve survival. To increase the power of this ob...
Yeom, Arim Ko, Eun Young Seo, Chorong Kim, Haejung Kim, Myoung Kyoung Han, Boo-Kyung Ko, Eun Sook Choi, Ji Soo
Published in
Academic radiology
This study aimed to identify the factors associated with malignant biopsy results for new lesions within one year after breast cancer surgery. This retrospective study included 192 lesions from 186 patients who underwent biopsy for newly developed breast lesions within one year of breast cancer surgery. All patients underwent breast ultrasound (US)...
Shen, Michelle García-Marqués, Fernando Muruganantham, Arvind Liu, Shiqin White, James Bermudez, Abel Rice, Meghan Thompson, Kelsey Chen, Chun-Liang Hung, Chia-Nung
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BACKGROUND: Despite nearly 100% 5-year survival for localised prostate cancer, the survival rate for metastatic prostate cancer significantly declines to 32%. Thus, it is crucial to identify molecular indicators that reflect the progression from localised disease to metastatic prostate cancer. METHODS: To search for molecular indicators associated ...