Li, Shanshan Fu, Xufeng Wang, Junfeng Yang, Hongju Wang, Dan Dong, Xudong Duan, Yanchao Wang, Hong Yan, Yaping Si, Wei
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Published in
Stem cell research & therapy
Liver fibrosis can progress to end-stage cirrhosis and liver cancer. Mesenchymal stem cells (MSCs) were considered the most promising therapeutic strategy, but most of the MSCs injected intravenously traditionally are trapped in the lungs, rapidly reducing their survival ability. MSC spheroids cultured in 3D have shown higher tolerance to fluid she...
Noguerol Álvarez, Mar Valer López Fando, Ma Paz Torrijos Bravo, Carolina Gómez Ortiz, Ma Carmen Piqueras Alcohol, Belén Guardiola Arévalo, Antonio De la Poza Gómez, Gema Pascual García, Zahara Rey Rodríguez, Sandra Iglesias Sigüenza, Raquel
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Published in
Gastroenterologia y hepatologia
To describe the proportion of patients with liver fibrosis in at-risk populations in primary care (PC). To know the agreement between FIB-4 and transitional elastography (TE), interobserver agreement between PC and hospital care (HC) in TE, and associated risk Factors (RF). Observational, descriptive, cross-sectional study in ≥16 years of age with ...
Peng, Bo Luo, Yulin Xie, Shudong Zhuang, Quan Li, Junhui Zhang, Pengpeng Liu, Kai Zhang, Yu Zhou, Chen Guo, Chen
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Published in
Parasite
Background: Schistosoma japonicum (S. japonicum) is the main species of Schistosoma prevalent in China. Myeloid-derived suppressor cells (MDSCs) are important immunoregulatory cells and generally expand in parasite infection, but there is little research relating to MDSCs in Schistosoma infection. Methods: Fifty-six S. japonicum-infected patients w...
Wang, Dapeng He, Rui Song, Qian Diao, Heng Jin, Ying Zhang, Aihua
Published in
Biological trace element research
Previous studies, including our own, have demonstrated that arsenic exposure can induce liver fibrosis, while the underlying mechanism remains unclear and there is currently no effective pharmacological intervention available. Recent research has demonstrated that vitamin D supplementation can ameliorate liver fibrosis caused by various etiologies,...
Pan, Binjing Zhao, Yangting Chen, Chongyang Cai, Jing Li, Kai Wang, Yawen Liu, Jingfang
Published in
Endocrine
To investigate the relationship between advanced liver fibrosis and osteoporosis in metabolic-associated fatty liver disease (MAFLD) in patients with type 2 diabetes mellitus (T2DM). A total of 1144 T2DM patients were divided into the MAFLD and non-MAFLD groups, 460 T2DM patients with MAFLD (277 males aged ≥50 years and 183 postmenopausal females) ...
Bicha, Samia Boumaraf, Habiba Lakehal, Abdelhak
Published in
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Traditionally, liver biopsy has been the gold standard for fibrosis staging. However, it is an invasive, expensive and uncomfortable procedure that is associated with the risk of complications. Thus, non-invasive methods such as shear wave elastography (SWE) have been developed as potential alternatives to liver biopsy. The aim of this study is to ...
Li, Zhao Yang, Hao Li, Xin She, Tianshan Tao, Ze Zhong, Yi Su, Tao Feng, Yanru Shi, Qiuxiao Li, Lin
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Published in
European journal of nuclear medicine and molecular imaging
Noninvasive quantifying activated hepatic stellate cells (aHSCs) by molecular imaging is helpful for assessing disease progression and therapeutic responses of liver fibrosis. Our purpose is to develop platelet-derived growth factor receptor β (PDGFRβ)-targeted radioactive tracer for assessing liver fibrosis by positron emission tomography (PET) im...
Kohla, Mohamed Ahmed Samy El Fayoumi, Ahmed Abdelsameea, Eman Elsabaawy, Maha Aly, Rasha Abdelhafiz Elkhadry, Sally Waheed Assem, Medhat
Published in
Romanian Journal of Internal Medicine
Background: Metabolic-associated fatty liver disease and liver fibrosis are intimately linked to insulin resistance, type 2 diabetes, obesity, and metabolic syndrome. Transient elastography (TE) and point shear wave elastography (pSWE) were used to measure liver stiffness in patients who met the ultrasound criteria for steatotic liver diseases (SLD...
Lv, Zhiyuan Song, Jianzhong Xiang, Yang Chen, Zhanghao Lu, Zinan Zhou, Quanqian Wang, Kaizhen Dahong, Hailiqian Taoer Zheng, Jiarui Zhang, Chunyu
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Published in
Fitoterapia
Alhagi honey is derived from the secretory granules of Alhagi pseudoalhagi Desv., a leguminous plant commonly known as camelthorn. Modern medical research has demonstrated that the extract of Alhagi honey possesses regulatory properties for the gastrointestinal tract and immune system, as well as exerts anti-tumor, anti-oxidative, anti-inflammatory...
Plaisy, Marie Kerbie Minga, Albert K Wandeler, Gilles Murenzi, Gad Samala, Niharika Ross, Jeremy Lopez, Alvaro Mensah, Ephrem de Waal, Renée Kuniholm, Mark H
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Published in
Journal of the International AIDS Society
Liver disease is a leading cause of morbidity and mortality among persons living with HIV (PLHIV). While chronic viral hepatitis has been extensively studied in low- and middle-income countries (LMICs), there is limited information about the burden of metabolic disorders on liver disease in PLHIV. We conducted a cross-sectional analysis of baseline...
