Coutinho, Rodrigo Hoshima, Henrique Yahagi Vianna, Marco Tadeu Gomes Marques, Marcia
Published in
Environmental science and pollution research international
The present study describes a set of methodological procedures (seldom applied together), including (i) development of an alternative adsorbent derived from abundant low-cost plant biomass; (ii) use of simple low-cost biomass modification techniques based on physical processing and chemical activation; (iii) design of experiments (DoE) applied to o...
Boughanem, Cécile Delaunay, Nathalie Pichon, Valérie
Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants of great concern due to their carcinogenicity and mutagenicity. Their determination in human serum, particularly in at-risk populations, is necessary but difficult because they are distributed over a wide range of polarity and are present at trace level. A new method combinin...
Karaki, Diana Dechaumet, Sylvain Damont, Annelaure Colsch, Benoit Fenaille, François Souloumiac, Antoine Thévenot, Etienne A
Liquid chromatography coupled to High-Resolution Mass Spectrometry (LC-HRMS) is the most widely used approach for the global detection of small molecules in biological samples (metabolomics). In complement to such MS1 data, structural identification of metabolites implies the acquisition of fragmentation spectra by performing tandem mass spectromet...
LIMA, M. dos S. MONTEIRO, L. I. da S. CARVALHO, A. J. de B. BASTOS, D. C. PIMENTEL, T. C. PIMENTEL, T. C. MAGNANI, M.
Reliable analytical methods are the basis for the elucidation of phenolic compounds in foods. This study aimed to optimize and validate a method for determining 42 phenolics using reverse-phase (RP) high-performance liquid chromatography (HPLC) coupled to diode-array-detector-DAD. The performance of two RP columns was eval- uated. The 150x4.6 mm 3-...
Kassahun, Haile; Van Schepdael, Ann; 16462; Ketema, Gebremariam; Adams, Erwin; 2122;
Antimicrobials, particularly antibiotics, are among the most common classes of drugs reported as substandard and falsified (SF) in developing countries. Therefore, it is important to develop simple and affordable analytical methods for the quality control of antimicrobial medicines. In this study, a liquid chromatographic method with ultraviolet de...
Roberts, David Loo, Joseph Tsybin, Yury Liu, Xiaowen Wu, Si Chamot-Rooke, Julia Agar, Jeffrey Paša-Tolić, Ljiljana Smith, Lloyd Ge, Ying
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Proteoforms, which arise from post-translational modifications, genetic polymorphisms and RNA splice variants, play a pivotal role as drivers in biology. Understanding proteoforms is essential to unravel the intricacies of biological systems and bridge the gap between genotypes and phenotypes. By analysing whole proteins without digestion, top-down...
Gallardo-Ramos, Jose Marín-Sáez, Jesús Sanchis, Vicente Gámiz-Gracia, Laura García-Campaña, Ana Hernández-Mesa, Maykel Cano-Sancho, Germán
esticides and mycotoxins, prominent chemical hazards in the food chain, are commonly found in plant-based foods, contributing to their pervasive presence in the human body, as evidenced by biomonitoring programs. Despite this, there is limited knowledge about their co-occurrence patterns. While intervention studies have demonstrated that organic di...
Akiyama, Tomoyuki Saigusa, Daisuke Inoue, Takushi Tokorodani, Chiho Akiyama, Mari Michiue, Rie Mori, Atsushi Hishinuma, Eiji Matsukawa, Naomi Shibata, Takashi
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Objective: The discovery of objective indicators for recent epileptic seizures will help confirm the diagnosis of epilepsy and evaluate therapeutic effects. Past studies had shortcomings such as the inclusion of patients under treatment and those with various etiologies that could confound the analysis results significantly. We aimed to minimize su...
Berska, Joanna Bugajska, Jolanta Sztefko, Krystyna
Published in
Annals of laboratory medicine
Antibiotic therapy requires appropriate dosage of drugs for effective treatment. Too low antibiotic concentrations may lead to treatment failure and the development of resistant pathogens, whereas overdosing may cause neurological side effects or hemolytic diseases. Meropenem and linezolid are used only in the treatment of serious infections or whe...
Ismail, Ghinwa El Hawari, Khaled Jaber, Farouk Verdon, Eric Al Iskandarani, Mohamad
Published in
Food additives & contaminants. Part B, Surveillance
Antimicrobials are administered in livestock for different uses leading to milk contamination and several undesirable effects. Because there is a lack of surveillance of antimicrobial residues (AMRs) in milk and dairy products in Lebanon, this study aims to determine the occurrence of AMRs in 90 Lebanese samples of milk and labneh (concentrated yog...
