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Synthesis of aromatic lactone analogues of Lipoxin A4

Published in BMC Research Notes

ObjectiveSynthesis of novel aromatic Lipoxin A4 lactone analogues.ResultsNovel para-substituted aromatic lactone analogues of Lipoxin A4 have been synthesized in a convergent manner with six steps in the longest linear sequence in 12–13% yields, employing 2-deoxy-d-ribose as a chiral pool starting material and the classical E-selective Wittig olefi...