Ma, Yun Guo, Guijie Li, Tingting Wen, Faxin Yang, Jianling Chen, Biao Wang, Xuefei Chen, Ji-Long
Published in
Molecular Cancer
BackgroundDysregulation of long noncoding RNAs (lncRNAs) has been linked to various human cancers. Bcr-Abl oncogene that results from a reciprocal translocation between human chromosome 9 and 22, is associated with several hematological malignancies. However, the role of lncRNAs in Bcr-Abl-induced leukemia remains largely unexplored.MethodsLncRNA c...
AlFayyad, Isamme Al-Tannir, Mohamad AlShammari, Amjad
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
To assess the prevalence and severity of clinically significant symptoms (CSSs) for breast cancer, colon cancer, and leukemia patients undergoing chemotherapy. A retrospective review of the Edmonton Symptom Assessment System scores reported by patients from the database of our previous large-scale study, which was collected between May 2018 and Jan...
Castelli, Lucia Elter, Thomas Wolf, Florian Watson, Matthew Schenk, Alexander Steindorf, Karen Bloch, Wilhelm Hallek, Michael Joisten, Niklas Zimmer, Philipp
...
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Sleep problems reported by hematological cancer patients are usually linked to higher levels of cancer-related fatigue. Although the awareness of sleep problems in solid cancer patients is rising, there has been less attention to the issue in hematological cancer patients. The present study assesses the differences in sleep by comparing physical ac...
Amanati, Ali Zekavat, Omid Reza Foroutan, Hamidreza Azh, Omidreza Tadayon, Ali Monabati, Ahmad Anbardar, Mohammad Hossein Bozorgi, Haleh
Published in
BMC Infectious Diseases
BackgroundBacterial enterocolitis is one of the most common neutropenic fever complications during intensive chemotherapy. Despite aggressive antibacterial treatments, this complication usually imposes high morbidity and mortality in cancer patients. Management of bacterial neutropenic enterocolitis are well known; however, management of fungal neu...
Cai, Baohuan Liu, Yun Chong, Yating Zhang, Hualei Matsunaga, Atsuko Fang, Xuexiu Pacholczyk, Rafal Zhou, Gang Cowell, John K. Hu, Tianxiang
...
Published in
Molecular Cancer
BackgroundStem Cell leukemia/lymphoma syndrome (SCLL) presents as a myeloproliferative disease which can progress to acute myeloid leukemia and is associated with the coincident development of B-cell and T-cell lymphomas. SCLL is driven by the constitutive activation of fibroblast growth factor receptor-1 (FGFR1) as a result of chromosome transloca...
Alabdulqader, Muneera Al Alawyat, Hanaa Kasem, Mohammed F. Ibrahim, Abdelfattah Omara, Abdelwahab
Published in
Renal Replacement Therapy
BackgroundHyperkalemia is a serious medical condition that requires immediate intervention. However, pseudohyperkalemia and reverse pseudohyperkalemia are misleading clinical manifestations that can result in incorrect diagnosis and consequent harmful intervention.Case presentationAn 11-year-old girl manifested an incidental finding of hyperleukocy...
Shimoda, Michiko Lyu, Yuanzhi Wang, Kang-Hsin Kumar, Ashish Miura, Hiroki Meckler, Joshua F Davis, Ryan R Chantarasrivong, Chanikarn Izumiya, Chie Tepper, Clifford G
...
In herpesvirus replicating cells, host cell gene transcription is frequently down-regulated because important transcriptional apparatuses are appropriated by viral transcription factors. Here, we show a small peptide derived from the Kaposi's sarcoma-associated herpesvirus transactivator (K-Rta) sequence, which attenuates cellular MYC expression, r...
Liu, Yin Chen, Yanling Dang, Lu Liu, Yixin Huang, Shisheng Wu, Sanyun Ma, Peixiang Jiang, Hongqiang Li, Yi Pan, Yunbao
...
Published in
Molecular Cancer
Dahariya, Swati Raghuwanshi, Sanjeev Sangeeth, Anjali Malleswarapu, Mahesh Kandi, Ravinder Gutti, Ravi Kumar
Published in
Cancer immunology, immunotherapy : CII
Acute megakaryocytic leukemia (AMKL) is one of the rarest sub-types of acute myeloid leukemia (AML). AMKL is characterized by high proliferation of megakaryoblasts and myelofibrosis of bone marrow, this disease is also associated with poor prognosis. Previous analyses have reported that the human megakaryoblastic cells can be differentiated into ce...
El-Hussieny, Marwa El-Sayed, Naglaa F Fouad, Marwa A Ewies, Ewies F
Published in
Bioorganic chemistry
Series of novel sulfonamide-based 3-indolinones 3a-m and 4a-f were designed, synthesized and then their cytotoxic activity was evaluated against a panel of sixty cancer cell lines. This screening indicated that 4-(2-(5-fluoro-2-oxoindolin-3-ylidene)acetyl)phenyl benzenesulfonate (4f) possessed promising cytotoxicity against CCRF-CEM and SR leukemia...
