Publication search
with Leptin action as keyword
Li, Rosa J.W. Zhang, Song-Yang Lam, Tony K.T.
Published in
Molecular Metabolism
Background In response to energy abundant or deprived conditions, nutrients and hormones activate hypothalamic pathways to maintain energy and glucose homeostasis. The underlying CNS mechanisms, however, remain elusive in rodents and humans. Scope of review Here, we first discuss brain glucose sensing mechanisms in the presence of a rise or fall of...
Scherer, Thomas Buettner, Christoph
Published in
Journal of Molecular Medicine
Endocannabinoids (ECs) are small lipid mediators that play a critical role in energy metabolism. Human studies have shown that the EC tone in peripheral tissues positively correlates with increased adiposity. Furthermore, pharmacological inhibition of EC signaling results in weight loss in humans. However, the mechanisms that cause the dysregulatio...
