The mystery of easter's island giants and their acromegalyc facies.
Published in Journal of endocrinological investigation
Effectiveness of self-care interventions for integrated morbidity management of skin neglected tropical diseases in Anam...
...Published in BMC Public Health
Background Lymphatic filariasis (LF), Buruli ulcer (BU) and leprosy are neglected tropical diseases (NTDs) of the skin co-endemic in some communities in Nigeria. Not enough is known about the effectiveness of integrated morbidity management and disability prevention in people with these conditions. An integrated self-care intervention was carried o...
Histoid leprosy presenting as a large tumor.
Published in Anais brasileiros de dermatologia
Histoid leprosy is a rare form of multibacillary leprosy, characterized by the presence of papules, plaques, or nodules whose appearance is keloid-like, skin colored, or erythematous. Fusiform cells are the main histopathological feature. Due to the fact that it can simulate other dermatological lesions, for example, dermatofibroma and neurofibroma...
Perception of cure among leprosy patients post completion of multi-drug therapy
Published in BMC Infectious Diseases
Background Leprosy is a treatable disease; however, the release from treatment after completion of multidrug therapy (MDT) often does not equal absence of health problems. Consequently, sequelae interfere with the patient’s perception of cure. The objective of this study was to analyze the factors associated with the perception of not being healed ...
Epidemiological profile of leprosy in the state of Mato Grosso: descriptive study
Published in Einstein
Objective To analyze the prevalence of leprosy cases using as parameters the number of diagnosed cases, age group, sex, clinical form of the disease, degree of physical disability, affected nerves, and therapeutic methods. Methods This was a descriptive study. Data were collected in the Information System for Notifiable Diseases ( Sistema de Inform...
Clinical prediction rules for the diagnosis of neuritis in leprosy
Published in BMC Infectious Diseases
Background Diagnosing neuritis in leprosy patients with neuropathic pain or chronic neuropathy remains challenging since no specific laboratory or neurophysiological marker is available. Methods In a cross-sectional study developed at a leprosy outpatient clinic in Rio de Janeiro, RJ, Brazil, 54 individuals complaining of neural pain (single or mul...
Factors associated to quality of life in patients with leprosy
Published in Einstein
Objective To evaluate quality of life and associated factors in patients with leprosy. Methods A cross-sectional study with 63 people diagnosed as leprosy, seen at a reference service for the disease in the southeastern region of Mato Grosso, Brazil. The questionnaire World Health Organization Quality of Life Bref was used to evaluate quality of li...
Histoid leprosy - A rare clinical presentation ☆ ☆☆
Published in Anais Brasileiros de Dermatologia
Histoid leprosy is considered a rare form of lepromatous leprosy. Its peculiar clinical picture makes its diagnosis a challenging one, which can delay starting treatment and perpetuate the disease as endemic. In addition to representing a reservoir of bacilli, and being an important means of contamination, these patients have greater resistance to ...
An individual randomised efficacy trial of autologous blood products, leukocyte and platelet-rich fibrin (L-PRF), to pro...
...Published in Trials
BackgroundLeprosy is curable with multidrug therapy and treatment in the early stages can prevent disability. However, local nerve damage can lead to injury and consequently recurring and disfiguring ulcers. The aim of this study is to evaluate the treatment of leprosy ulcers using an autologous blood product; leukocyte and platelet-rich fibrin (L-...
Association of the polymorphism of the vitamin D receptor gene ( VDR ) with the risk of leprosy in the Brazilian Amazon
Published in Bioscience Reports
The transmission and evolution of leprosy depends on several aspects, including immunological and genetic factors of the host, as well as genetic factors of Mycobacterium leprae . The present study evaluated the association of single nucleotide polymorphisms (SNPs) on the FokI (rs2228570), TaqI (rs731236), ApaI (rs7975232) regions of the vitamin D ...
