Published in Global public health
Leprosy stigma is more neglected than the disease itself since global interventions towards leprosy are focused on the medicalisation of individual-sufferers and statistical counting of documented cases and less prioritising the impact of leprosy stigma towards society. This paper examines the impact of courtesy stigma on society through comparativ...
Published in Infectious Diseases of Poverty
BackgroundLeprosy can be cured, but physical disability (PD) as a result of the infection can progress in the post-release from treatment phase. This study evaluated the likelihood of, and factors associated with, the progression of the PD grade post-release from treatment among leprosy patients treated in Cáceres-MT, Brazil in the period 2000 to 2...
Published in Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Intra-domiciliary contacts are a group with the highest risk of developing leprosy. METHODS A cross-sectional study of intra-domiciliary contacts of new leprosy cases was conducted. A descriptive analysis of the variables was performed. RESULTS Among 190 contacts, 63% were invited to visit the health unit, and 54.2% received the BCG va...
Published in Heliyon
Health Sciences; Infectious Disease; Medical Microbiology; Clinical Research; Diagnostics; Biomarkers; Leprosy; leprosy reaction; neutrophil-to-lymphocyte ratio; diagnosis; biomarker
Published in Infectious Diseases of Poverty
BackgroundMycobacterium leprae and Toxoplasma gondii infections are both neglected tropical diseases highly prevalent in Brazil. Infection with certain parasite species can significantly alter susceptibility to other important pathogens, and/or influence the development of pathology. Here we investigated the possible influence of M. leprae/T. gondi...
Die Geschichte der Lepra ist geprägt von Elend, Siechtum und Ausgrenzung bis hin zum Pogrom, aber andererseits auch von religiöser Überhöhung, Privilegierung und beispielhafter Fürsorge. Diese Ambivalenz ist sehr typisch für den Umgang mit Leprakranken, auch Leprose genannt, im Mittelalter und in der frühen Neuzeit. Und sie spiegelt sich auch in Vo...
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene
Although multidrug therapy (MDT) has been widely used for the treatment of leprosy for nearly 40 y, the disease remains a public health concern in some areas. The early detection of leprosy cases is vital to interrupt Mycobacterium leprae transmission, but currently diagnosis is typically achieved during the recognition of clinical symptoms by prof...
Abstract This ecological study aims to analyze both the tendency and the characteristics of leprosy in the elderly population in the state of Bahia, 2001-2017. The tendency was analyzed through joinpoint regression. Epidemiological variables were also included in the study. The average detection rate was 38.73/100,000, with prevalence of men (45.19...
Abstract Background and objectives: Leprosy remains a leading cause of peripheral neuropathy and disability in the world. Primary objective of the study was to determine the incidence of deformities present at a time of diagnosis and new deformities that patients develop over follow up period. Material and methods: An open, retrospective cohort stu...
Published in F1000Research
Chronic infection by the obligate intracellular pathogen Mycobacterium leprae may lead to the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of the immune system to constrain infection allows the pathogen to reproduce to very high numbers with minimal clinical signs, favoring transmission. The bacillus can...
