Ehrlich, Kristina Morbach, Caroline Reiter, Theresa Heuschmann, Peter Ulrich Hannemann, Anke Fassnacht, Martin Störk, Stefan Hahner, Stefanie Deutschbein, Timo
Published in
BMC Endocrine Disorders
BackgroundEndogenous Cushing’s syndrome (CS) results in increased cardiovascular (CV) morbidity and mortality. So far, most studies focussed on distinct disease entities rather than the integrity of the CV system. We here describe the design of the Cardiovascular Status in Endogenous Cortisol Excess Study (CV-CORT-EX), a study aiming to comprehensi...
Park, Kyungil Park, Tae-Ho Jo, Yoon-Seong Cho, Young-Rak Park, Jong-Sung Kim, Moo-Hyun Kim, Young-Dae
Published in
Cardiovascular Ultrasound
BackgroundIt is unclear whether increased left ventricular (LV) thickness is associated with worse clinical outcomes in severe aortic stenosis (AS). The aim of this study was to determine the effect of increased LV wall thickness (LVWT) on major clinical outcomes in patients with severe AS.Methods and resultsThis study included 290 severe AS patien...
Kianu Phanzu, Bernard Nkodila Natuhoyila, Aliocha Kintoki Vita, Eleuthère M’Buyamba Kabangu, Jean-René Longo-Mbenza, Benjamin
Published in
BMC Cardiovascular Disorders
BackgroundConflicting information exists regarding the association between insulin resistance (IR) and left ventricular hypertrophy (LVH). We described the associations between obesity, fasting insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), and LVH in Black patients with essential hypertension.MethodsA case–control study...
Fuller, Maria Perry, Rebecca Saiedi, Madiha Fletcher, Janice M. Selvanayagam, Joseph B.
Published in
Molecular Genetics and Metabolism Reports
Fabry disease (FD) results from a deficiency in the exoglycohydrolase, α-galactosidase A (AGA), an enzyme required for the sequential degradation of glycosphingolipids, which consequently accumulate in the lysosomes of affected cells. An X-linked inherited metabolic disorder, FD has a high incidence of a later onset phenotype that is under-diagnose...
Velicki, Lazar Jakovljevic, Djordje G. Preveden, Andrej Golubovic, Miodrag Bjelobrk, Marija Ilic, Aleksandra Stojsic, Snezana Barlocco, Fausto Tafelmeier, Maria Okwose, Nduka
...
Published in
BMC Cardiovascular Disorders
BackgroundHypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disease that affects approximately one in 500 people. HCM is a recognized genetic disorder most often caused by mutations involving myosin-binding protein C (MYBPC3) and β-myosin heavy chain (MYH7) which are responsible for approximately three-quarters of the id...
Zhang, Zhen Xie, Yeqing Shen, Bo Nie, Yuxin Cao, Xuesen Xiang, Fangfang Zou, Jianzhou
Published in
Blood purification
Left ventricular hypertrophy (LVH) is a highly prevalent presentation of cardiac structural abnormality and a strong predictor of adverse outcomes in maintenance hemodialysis (MHD) patients. Different left ventricular geometry may provide additional clinical information. Soluble ST2 is a novel cardiac prognostic biomarker in MHD patients and is clo...
Dörr, Oliver Liebetrau, Christoph Weferling, Maren Hoffmann, Felix Forderer, Nicolas Keller, Till Boeder, Niklas Blachutzik, Florian Keranov, Stanislav Bauer, Pascal
...
Published in
Herz
Fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) has been validated in patients with stable coronary artery disease (CAD) but has not yet been verified under specific conditions such as heart failure or microvascular dysfunction. The aim of the present study was to examine the influence of specific patient comorbidities...
Yu, Lei Li, Huajun Liu, Xianbao Fan, Jiaqi Zhu, Qifeng Li, Jing Jiang, Jubo Wang, Jian'an
Published in
Herz
Ein obstruktives Schlafapnoesyndrom führt zur Vorhofdilatation, linksventrikulären Hypertrophie, Vergrößerung, Massenzunahme und Abnahme der systolischen Funktion. Die Behandlung eines OSAS könnte sich günstig auf den Erhalt der Linksherzstruktur und -funktion auswirken.
Sendzikaite, Skaiste Sudikiene, Rita Tarutis, Virgilijus Lubaua, Inguna Silis, Pauls Rybak, Agata Jankauskiene, Augustina Litwin, Mieczyslaw
Published in
Pediatric nephrology (Berlin, Germany)
This study aimed to evaluate hemodynamic phenotypes and prevalence of left ventricular hypertrophy in children after coarctation repair with right arm and leg blood pressure difference
Talib, Ali Roebroek, Yvonne G M Paulus, Givan F van Loo, Kris Winkens, Bjorn Bouvy, Nicole D van Heurn, Ernst L W E
Published in
Pediatric cardiology
Left ventricular hypertrophy (LVH) is independently associated with a higher risk of cardiovascular morbidity and mortality in adults. Adiposity is a risk factor for LVH, independent of blood pressure. Potential causes of this nonhemodynamic pathogenesis identified in adults include adverse body fat distribution, insulin resistance, dyslipidemia, a...
