An objective hemodynamic assessment is mandatory to confirm Critical Limb Ischemia (CLI). Toe pressure measurement is recommended. We compared toe measurements obtained using the Laser Doppler method (LD) (PERIMED PeriFlux, Sweden) considered as the reference test, with those obtained with a portable device using photoplethysmography (PPG) (Sys Toe...
Published in Burns : journal of the International Society for Burn Injuries
Skin breakdown, as in wounds, leads to an electric potential, defined as current of injury with the intent of wound closure. Burn wounds are defined by different zones of perfusion having a direct influence on further therapy (e.g. conservative management or skin grafting). We studied immediate, quantifiable effects of electric stimulation on skin ...
PURPOSE: Anterior resection is the procedure of choice for tumours in the mid and upper rectum. Depending on tumour height, a total mesorectal excision (TME) or partial mesorectal excision (PME) can be performed. Low anastomoses in particular have a high risk of developing anastomotic leakage, which might be explained by blood perfusion compromise....
Published in Microvascular Research
• State-of-the-art non-invasive imaging methods provide new insights into the pathophysiology of SSc-spectrum disorders. • In ‘SSc fingers’, perfusion correlates positively with oxygenation, and capillary density negatively with skin thickness. • This study further confirms that fibrosis and microvascular changes are key elements of the SSc disease...
Published in Clinical rheumatology
Digital ulcers (DUs) represent one major burden for patients with systemic sclerosis (SSc). The objectives of our study were to evaluate blood flow in SSc-DUs with laser speckle contrast analysis (LASCA) and to correlate the skin perfusion to clinical and laboratory data. Forty DUs in 31 consecutive patients with SSc according to 2013 ACR/EULAR cri...
Published in European Journal of Applied Physiology
PurposeChildren thermoregulate effectively during exercise despite sweating rate being consistently lower when compared with adults. The skin blood flow (SkBF) response of children to exercise is inconsistent, when compared with adults. We examined the SkBF response to exercise in children and adults, along with the potential contribution of nitric...
Published in European Journal of Applied Physiology
Several techniques exist for the determination of skin blood flow that have historically been used in the investigation of thermoregulatory control of skin blood flow, and more recently, in clinical assessments or as an index of global vascular function. Skin blood flow measurement techniques differ in their methodology and their strengths and limi...
This PhD aimed at introducing laser Doppler holography (LDH) into the field of ophthalmology in order to image blood flow in the eye posterior pole. Perfusion abnormalities play a central role in the development of ocular pathologies, which calls for the development of suitable instruments to elucidate it. LDH had previously demonstrated its abilit...
Objectifs : L’objectif principal de l’étude est d’évaluer la répétabilité et la reproductibilité à court terme de la mesure des pressions digitales en laser Doppler entre un manchon placé sur la 1ère ou sur la 2ème phalange. Les objectifs secondaires sont de comparer la reproductibilité entre la prise de 2 ou 3 mesures à chaque doigt et la corrélat...
Published in Journal of Vascular Research
Background: Arteriovenous fistulae impair the distal circulation, but their effects at the microcirculatory level are not well understood. This study presents the carotid-jugular fistula (CJF) as a model to evaluate fistula-related microcirculatory and systemic changes. Materials and Methods: Female Wistar rats were anesthetized and divided into a ...
