Wang, Zhi-Bin Qu, Jian Xie, Pan Yang, Zhi-Quan Mao, Chen-Xue Zhang, Ying He, Zheng-Wen Yang, Zhuan-Yi Mao, Xiao-Yuan Liu, Zhao-Qian
...
Published in
BMC Genomics
Background Seizures are a common symptom in glioma patients, and they can cause brain dysfunction. However, the mechanism by which glioma-related epilepsy (GRE) causes alterations in brain networks remains elusive. Objective To investigate the potential pathogenic mechanism of GRE by analyzing the dynamic expression profiles of microRNA/ mRNA/ lncR...
russ;, hermann
Soluble amyloid β (Aβ) oligomers have been shown to be highly toxic to neurons and are considered to be a major cause of the neurodegeneration underlying Alzheimer’s disease (AD). That makes soluble Aβ oligomers a promising drug target. In addition to eliminating these toxic species from the patients’ brain with antibody-based drugs, a new class of...
Gonzalez-Klein, Zulema Pazos-Castro, Diego Hernandez-Ramirez, Guadalupe Garrido-Arandia, Maria Diaz-Perales, Araceli Tome-Amat, Jaime
Published in
Frontiers in Allergy
Lipid Transfer Proteins (LTPs) have been described as one of the most prevalent and cross-reactive allergen families in the general population. They are widely distributed among the plant kingdom, as well as in different plant organs ranging from pollen to fruits. Thus, they can initiate allergic reactions with very different outcomes, such as asth...
Yu, Jinzheng Zhu, Ligu
Published in
ITM Web of Conferences
With the prominence of the “emotion setting” function in media agenda setting, the sentiment bias of netizens has gradually become a noteworthy part of the communication of public opinion events. In this paper, we use the BERT model to analyze the sentiment of news headlines and netizens’ comments from January 2021 to July 2021, and extract news he...
Huertas, Marco A. Newton, Adam J. H. McDougal, Robert A. Sacktor, Todd Charlton Shouval, Harel Z.
Published in
eNeuro
Activity-dependent modifications of synaptic efficacies are a cellular substrate of learning and memory. Experimental evidence shows that these modifications are synapse specific and that the long-lasting effects are associated with the sustained increase in concentration of specific proteins like PKM ζ . However, such proteins are likely to diffus...
Ma, Shaorong Zuo, Yi
Published in
Seminars in cell & developmental biology
Synapses are specialized sites where neurons connect and communicate with each other. Activity-dependent modification of synaptic structure and function provides a mechanism for learning and memory. The advent of high-resolution time-lapse imaging in conjunction with fluorescent biosensors and actuators enables researchers to monitor and manipulate...
Stern-Mentch, Naama Bostwick, Gabrielle Winters Belenky, Michael Moroz, Leonid Hochner, Binyamin
Published in
Journal of morphology
The vertical lobe (VL) in the octopus brain plays an essential role in its sophisticated learning and memory. Early anatomical studies suggested that the VL is organized in a "fan-out fan-in" connectivity matrix comprising only three morphologically identified neuron types; input axons from the median superior frontal lobe (MSFL) innervating en pas...
Brandalise, Federico Carta, Stefano Leone, Roberta Helmchen, Fritjof Holtmaat, Anthony Gerber, Urs
Published in
Neuroscience
N-methyl-d-aspartate receptor-mediated ( spikes can be causally linked to the induction of synaptic long-term potentiation (LTP) in hippocampal and cortical pyramidal cells. However, it is unclear if they regulate plasticity at a local or global scale in the dendritic tree. Here, we used dendritic patch-clamp recordings and calcium imaging to inves...
Pauliat Desbordes, S. Challier, P. Trividic, T. Choël, M. Chantran, Y. Selva, M.A. Broussard, C. Sénéchal, H. Poncet, P.
But de l’étudeL’acérola est un fruit tropical 20 à 30 fois plus riche en vitamine C que l’orange. On trouve de l’acérola dans des comprimés ou des poudres vendus pour leur richesse en vitamine C et aussi sous forme de jus ou en additif dans des compotes ou jus de fruit. Excepté la mise en évidence d’une réactivité croisée d’une protéine non identif...
Stacho, Martin Manahan-Vaughan, Denise
Published in
Frontiers in Behavioral Neuroscience
Long-term potentiation (LTP) and long-term depression (LTD) comprise the principal cellular mechanisms that fulfill established criteria for the physiological correlates of learning and memory. Traditionally LTP, that increases synaptic weights, has been ascribed a prominent role in learning and memory whereas LTD, that decreases them, has often be...
