Sequential shear-wave elastography of liver and spleen rules out clinically significant portal hypertension in compensat...
Published in Gut
Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis.
...Published in Gut
Hepatic JAK2/ARHGEF1/ROCK expression is associated with portal hypertension and decompensation in human cirrhosis. The deletion of Jak2 in myofibroblasts attenuated experimental fibrosis and acute inhibition of JAK2 decreased PP. Thus, JAK2 inhibitors, already in clinical use for other indications, might be a new approach to treat cirrhosis with po...
A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular c...
...Published in Gut
This work highlights the unique transcriptional niche of stellate cells, and identifies potential stellate cell targets for tracking, targeting and isolation. Hepatic stellate cell signature expression may identify patients with HCV cirrhosis or postresection HCC with poor prognosis.
A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular c...
...Published in Gut
This work highlights the unique transcriptional niche of stellate cells, and identifies potential stellate cell targets for tracking, targeting and isolation. Hepatic stellate cell signature expression may identify patients with HCV cirrhosis or postresection HCC with poor prognosis.
Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.
...Published in Gut
AH is characterised by a deregulated miRNA profile, including miR-182, which is associated with disease severity and liver injury. These results highlight the potential of miRNAs as therapeutic targets and biomarkers in AH.
Is human albumin solution really the best resuscitation fluid for patients with advanced cirrhosis?
Published in Gut
Beta-blockers in patients with cirrhosis and ascites: type of beta-blocker matters.
Published in Gut
Red signs and not severity of cirrhosis should determine non-selective β-blocker treatment in Child-Pugh C cirrhosis wit...
Published in Gut
Algorithm to rule out clinically significant portal hypertension combining Shear-wave elastography of liver and spleen: ...
...Published in Gut
The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurement...
Published in Gut
