Introduction. An in vivo determination of bile acid hepatobiliary transport efficiency can be of use in liver disease and preclinical drug development. Given the increased interest in bile acid Positron Emission Tomography- (PET-) imaging, a further understanding of the impact of 18-fluorine substitution on bile acid handling in vitro and in vivo c...
Introduction. An in vivo determination of bile acid hepatobiliary transport efficiency can be of use in liver disease and preclinical drug development. Given the increased interest in bile acid Positron Emission Tomography- (PET-) imaging, a further understanding of the impact of 18-fluorine substitution on bile acid handling in vitro and in vivo c...
Introduction. An in vivo determination of bile acid hepatobiliary transport efficiency can be of use in liver disease and preclinical drug development. Given the increased interest in bile acid Positron Emission Tomography- (PET-) imaging, a further understanding of the impact of 18-fluorine substitution on bile acid handling in vitro and in vivo c...
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Published in Journal of cellular biochemistry
Nonsense-mediated mRNA decay (NMD) degrades mRNAs carrying a premature termination codon (PTC) in eukaryotes. Cellular stresses, including endoplasmic reticulum (ER) stress, inhibit NMD, and up-regulate PTC-containing mRNA (PTC-mRNA) levels in several cell lines. However, whether similar effects exist under in vivo conditions that involve systemic ...
The liver is one of the most injured organs in road or domestic accidents. To protect or repair it, companies and clinicians rely more and more on numerical finite elements models. It is highly complex owing to its structure, its dual blood supply and its environment. It is located under the diaphragm and partially covered by the thoracic cage and ...
The liver is one of the most injured organs in road or domestic accidents. To protect or repair it, companies and clinicians rely more and more on numerical finite elements models. It is highly complex owing to its structure, its dual blood supply and its environment. It is located under the diaphragm and partially covered by the thoracic cage and ...
The liver is one of the most injured organs in road or domestic accidents. To protect or repair it, companies and clinicians rely more and more on numerical finite elements models. It is highly complex owing to its structure, its dual blood supply and its environment. It is located under the diaphragm and partially covered by the thoracic cage and ...
Published in Gut
The risks of poor transition include delayed and inappropriate transfer that can result in disengagement with healthcare. Structured transition care can improve control of chronic digestive diseases and long-term health-related outcomes. These are the first nationally developed guidelines on the transition of adolescent and young persons (AYP) with...
Published in Journal of cellular biochemistry
Herpes simplex viruses can cause uncommon systemic complications as acute liver failure (ALT) or urinary tract dysfunctions. Diphenyl diselenide, (PhSe)2 , a classical studied organic selenium compound, has a novel antiviral action against HSV-2 infection and well-known antioxidant and anti-inflammatory properties. This study aimed to investigate i...
