Harada, Nagakatsu Okuyama, Maiko Yoshikatsu, Aya Yamamoto, Hironori Ishiwata, Saori Hamada, Chikako Hirose, Tomoyo Shono, Masayuki Kuroda, Masashi Tsutsumi, Rie
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Published in
Journal of cellular biochemistry
Nonsense-mediated mRNA decay (NMD) degrades mRNAs carrying a premature termination codon (PTC) in eukaryotes. Cellular stresses, including endoplasmic reticulum (ER) stress, inhibit NMD, and up-regulate PTC-containing mRNA (PTC-mRNA) levels in several cell lines. However, whether similar effects exist under in vivo conditions that involve systemic ...
Brooks, Alenka J Smith, Philip J Cohen, Richard Collins, Paul Douds, Andrew Forbes, Valda Gaya, Daniel R Johnston, Brian T McKiernan, Patrick J Murray, Charles D
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Published in
Gut
The risks of poor transition include delayed and inappropriate transfer that can result in disengagement with healthcare. Structured transition care can improve control of chronic digestive diseases and long-term health-related outcomes. These are the first nationally developed guidelines on the transition of adolescent and young persons (AYP) with...
Sartori, Gláubia Jardim, Natália Silva Sari, Marcel Henrique Marcondes Flores, Eduardo F Prigol, Marina Nogueira, Cristina W
Published in
Journal of cellular biochemistry
Herpes simplex viruses can cause uncommon systemic complications as acute liver failure (ALT) or urinary tract dysfunctions. Diphenyl diselenide, (PhSe)2 , a classical studied organic selenium compound, has a novel antiviral action against HSV-2 infection and well-known antioxidant and anti-inflammatory properties. This study aimed to investigate i...
Sartori, Gláubia Jardim, Natália Silva Sari, Marcel Henrique Marcondes Flores, Eduardo F Prigol, Marina Nogueira, Cristina W
Published in
Journal of cellular biochemistry
Herpes simplex viruses can cause uncommon systemic complications as acute liver failure (ALT) or urinary tract dysfunctions. Diphenyl diselenide, (PhSe)2 , a classical studied organic selenium compound, has a novel antiviral action against HSV-2 infection and well-known antioxidant and anti-inflammatory properties. This study aimed to investigate i...
Van Baeten, Chris Van Dorpe, Jo
Splenic inflammatory pseudotumor (IPT) is an uncommon lesion with an inflammatory morphologic aspect that often poses a diagnostic challenge. The etiology of IPT can be infectious, autoimmune, reactive, or neoplastic. Splenic Epstein-Barr virus (EBV)-associated IPTs form a subset of splenic IPTs in which there is a spindle cell component infected b...
Liu, Boyan Cao, Lili Zhang, Lijun Yuan, Xiaofan Zhao, Bing
Eupatorium adenophorum can induce liver toxicity in animals. For the safe utilisation of the weed, the hepatotoxic components need to be discovered. In this study, in vitro hepatotoxicity of different extracts from E. adenophorum were determined on human hepatocyte cell line L02 and hepatocellular carcinoma cell line HepG2. The results showed that ...
Antonissen, Gunther Devreese, Mathias De Baere, Siegrid Martel, An Van Immerseel, Filip Croubels, Siska
Timmermans, Steven Van Montagu, Marc Libert, Claude
Mouse inbred strains remain essential in science. We have analyzed the publicly available genome sequences of 36 popular inbred strains and provide lists for each strain of protein-coding genes that acquired sequence variations that cause premature STOP codons, loss of STOP codons and single nucleotide polymorphisms, and short in-frame insertions a...
Vercauteren, Koen Brown, Richard J P Mesalam, Ahmed Atef Doerrbecker, Juliane Bhuju, Sabin Geffers, Robert Van Den Eede, Naomi McClure, C Patrick Troise, Fulvia Verhoye, Lieven
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Published in
Gut
This study provides preclinical in vivo evidence that addition of an entry inhibitor to an anti-HCV DAA regimen restricts the breakthrough of DAA-resistant viruses. Our approach is an excellent strategy to prevent therapeutic failure caused by on-therapy rebound of DAA-RAVs. Inclusion of an entry inhibitor to the newest DAA combination therapies ma...
Suk, Ki-Tae Mederacke, Ingmar Gwak, Geum-Youn Cho, Sung Won Adeyemi, Adebowale Friedman, Richard Schwabe, Robert F
Published in
Gut
Similar to their role in fibrogenesis, CB1 and CB2 exert opposite effects on hepatocarcinogenesis and may provide novel therapeutic targets.
