Cytogenetic and molecular aberrations and worse outcome for male patients in systemic mastocytosis
...
status: published
Prognostic impact of eosinophils in mastocytosis: analysis of 2350 patients collected in the ECNM Registry
...
Systemic mastocytosis (SM) is frequently associated with eosinophilia. To examine its prevalence and clinical impact in all WHO classification-based subcategories, we analyzed eosinophil counts in 2350 mastocytosis patients using the dataset of the European Competence Network on Mastocytosis. Ninety percent of patients had normal eosinophil counts,...
Geographic distribution and environmental risk factors of lymphoma in dogs under primary-care in the UK.
OBJECTIVES: To integrate external data sources with VetCompass postcode data to explore the spatial distribution and examine potential associations with environmental risk factors in dogs diagnosed with lymphoma at primary care veterinary practices. MATERIALS AND METHODS: Cases of lymphoma were identified from electronic patient records of 455,553 ...
Providing both autologous and allogeneic hematopoietic stem cell transplants (HSCT) may have a stronger impact on the ou...
...Published in Bone marrow transplantation
While performance since the introduction of the JACIE quality management system has been shown to be improved for allogeneic hematopoietic stem cell transplants (HSCT), impact on autologous-HSCT remains unclear in Europe. Our study on 2697 autologous-HSCT performed in adults in 17 Belgian centres (2007-2013) aims at comparing the adjusted 1 and 3-y...
Granulocyte colony-stimulating factor and respiratory status of critically ill neutropenic patients with hematologic mal...
...Published in Leukemia & lymphoma
In patients with hematologic malignancies, respiratory status may deteriorate during neutropenia recovery. This multicenter, observational study aims to evaluate granulocyte colony-stimulating factor (G-CSF) impact on respiratory status in critically ill neutropenic patients. Among 1011 critically ill patients with hematologic malignancies, 288 wer...
Providing both autologous and allogeneic hematopoietic stem cell transplants (HSCT) may have a stronger impact on the ou...
...
While performance since the introduction of the JACIE quality management system has been shown to be improved for allogeneic hematopoietic stem cell transplants (HSCT), impact on autologous-HSCT remains unclear in Europe. Our study on 2697 autologous-HSCT performed in adults in 17 Belgian centres (2007-2013) aims at comparing the adjusted 1 and 3-y...
Do a humanoid robot and music increase the motivation to perform physical activity? : a quasi-experimental cohort in typ...
Background: It can be difficult to motivate children to participate in physical exercises, especially when they have oncological disorders. Purpose: examine the effect of a humanoid robot and music on motivation to participate in physical activity in typically developing children (TDC) and children with oncological disorders (COD). Methods: Two coh...
Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute ...
...Published in British journal of haematology
Data on occurrence, genetic characteristics and prognostic impact of complex and monosomal karyotype (CK/MK) in children with acute myeloid leukaemia (AML) are scarce. We studied CK and MK in a large unselected cohort of childhood AML patients diagnosed and treated according to Nordic Society for Paediatric Haematology and Oncology (NOPHO)-AML prot...
Drosophila melanogaster as a function-based high-throughput screening model for antinephrolithiasis agents in kidney sto...
...
Kidney stone disease involves the aggregation of stone-forming salts consequent to solute supersaturation in urine. The development of novel therapeutic agents for this predominantly metabolic and biochemical disorder have been hampered by the lack of a practical pre-clinical model amenable to drug screening. Here, Drosophila melanogaster, an emerg...
Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young w...
...Published in Scientific Reports
MiRNAs are part of the epigenetic machinery, and are also epigenetically modified by DNA methylation. MiRNAs regulate expression of different genes, so any alteration in their methylation status may affect their expression. We aimed to identify methylation differences in miRNA encoding genes in breast cancer affecting women under 35 years old (BCVY...
