Tasdan, Zeynep Avci, Gülçin Alp Avci, Emre
Published in
Acta Marisiensis - Seria Medica
Objective: Cancer is one of the most important diseases today. The use of chemical drugs, surgical operations, and transplants is very common in its treatment. In addition to these treatment methods, studies include the effects of natural and plant-derived substances. Various substances are used in these studies, which are called phytotherapy. The ...
Gruber-Bzura, Beata M Bubko, Irena Sztybor, Paulina Piechocińska, Julia Drozd, Ewa
Published in
Biopreservation and biobanking
Objective: Inappropriate handling of cells can generate modifications in the genomic DNA. The additional risk is cross-contamination. Isoenzyme analysis with gel agarose electrophoresis is a known, fast, and cheap technique for detection of species-specific isoforms of intracellular enzymes. The aim of the experimental work was to check if variatio...
bunea;, mihaela-cristina
Azathioprine (AZA) is a pharmacologic immunosuppressive agent administrated in various conditions such as autoimmune disease or to prevent the rejection of organ transplantation. The mechanism of action is based on its biologically active metabolite 6-mercaptopurine (6-MP), which is converted, among others, into thioguanine nucleotides capable of i...
Tesse, Angela André, Franck M. Ragot, Thierry
Published in
Scientific Reports
Gene electrotransfer is an attractive method of non-viral gene delivery. However, the mechanism of DNA penetration across the plasma membrane is widely discussed. To explore this process for even larger structures, like viruses, we applied various combinations of short/long and high/low-amplitude electric pulses to L929 cells, mixed with a human ad...
Padilha Fontoura, Cristian Ló Bertele, Patrícia Machado Rodrigues, Melissa Elisa Dotta Maddalozzo, Ana Frassini, Rafaele Silvestrin Celi Garcia, Charlene Tomaz Martins, Sandro Crespo, Janaina da Silva Figueroa, Carlos A Roesch-Ely, Mariana
...
Published in
ACS biomaterials science & engineering
Ti6Al4V is one of the most lightweight, mechanically resistant, and appropriate for biologically induced corrosion alloys. However, surface properties often must be tuned for fitting into biomedical applications, and therefore, surface modification is of paramount importance to carry on its use. This work compares the interaction between two differ...
havrdová;, markéta
It is important to understand the nanomaterials intracellular trafficking and distribution and investigate their targeting into the nuclear area in the living cells. In our previous study, we firstly observed penetration of nonmodified positively charged carbon dots decorated with quaternary ammonium groups (QCDs) into the nucleus of mouse NIH/3T3 ...
Tai, Hitoshi Su, Hongru Takamoto, Naoya Fujita, Hiromi Takano, Ai Oishi, Saori Abe, Fuyuki Ando, Shuji Ohashi, Norio
Published in
Japanese journal of infectious diseases
Non-pathogenic Rickettsia species LON strains closely related to an agent of Japanese spotted fever (JSF), R. japonica, were isolated in Japan from Haemaphysalis longicornis ticks in 2001. However, the biological properties of LONs in mammalian host cells are poorly understood. In this study, microscopic analysis showed that LONs in a mouse-derived...
Schmitz, Werner Koderer, Corinna El-Mesery, Mohamed Gubik, Sebastian Sampers, Rene Straub, Anton Kübler, Alexander Christian Seher, Axel
Published in
International Journal of Molecular Sciences
Since Otto Warburg reported in 1924 that cancer cells address their increased energy requirement through a massive intake of glucose, the cellular energy level has offered a therapeutic anticancer strategy. Methionine restriction (MetR) is one of the most effective approaches for inducing low-energy metabolism (LEM) due to the central position in m...
Reis, R Sipahi, H Dinc, O Kavaz, T Charehsaz, M Dimoglo, A Aydın, A
Published in
Human & experimental toxicology
Over the last decade, electrolyzed water (EW) produced by salt and tap water has gained importance due to its antimicrobial effects. Regarding to chlorine-based compounds, EW also used in post-harvest safety of food processing and sterilization of surfaces. The latest studies suggested that EW might act as wound healing agent due to anti-infective ...
Rakhshandeh, Hassan Rashidi, Roghayeh Vahedi, Mohammad Mahdi Khorrami, Mohammad Bagher Abbassian, Hassan Forouzanfar, Fatemeh
Published in
Recent patents on food, nutrition & agriculture
Sleep disorders are among the most common psychiatric and medical conditions. Herbal medicine appears to be effective in the treatment of sleep disorders which have been valued by many of publications and patents. The present study aimed at investigating the hypnotic activity of the hydro-alcoholic extract of Capparis spinosa (HAE) in mice. Three d...
