Published in BMC Research Notes
ObjectiveWe explored detrimental effects of VCD on non-ovarian tissues such as kidneys and liver 14 days post-drug administration. Twelve rats were randomly assigned into two groups. In VCD group, rats received 160 mg/kgbw VCD intraperitoneally for 15 consequent days. Control rats were injected with VCD-free normal saline. At the respective time po...
Published in Rechtsmedizin
In der Literatur sind seit vielen Jahren histopathologische Nierenbefunde bei Drogensüchtigen beschrieben worden. Klinisch sind – wenn auch relativ selten – drogenbedingte akute nephrotische Syndrome bis zur Dialysepflichtigkeit bekannt. Die zugrunde liegenden pathophysiologischen Prozesse sind nur teilweise bekannt, im Vordergrund steht weniger di...
Published in Environmental Science and Pollution Research
Tartrazine is one of the most widely used food additives. The present investigation was carried out on 40 adult male albino rats. They were divided into four groups of ten animals for each. Group I was considered as a control group. Group II was treated with tartrazine daily in a dose 7.5 mg/kg body weight by oral gavage for 30 days. Group III was ...
Published in Pediatric Radiology
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. This pathology has been increasingly diagnosed in utero and several sonographic patterns are well described in the literature.ObjectiveTo present a series of fetuses with an unusual imaging pattern of ADPKD, mimicking autosomal recessive polyc...
Published in Current Urology Reports
Purpose of ReviewIn this article, we describe the basics of how magnetic resonance urography (MRU) is performed in the pediatric population as well as the common indications and relative performance compared to standard imaging modalities.Recent FindingsAlthough MRU is still largely performed in major academic or specialty imaging centers, more and...
International audience
Published in EJNMMI Physics
BackgroundPeptide receptor radionuclide therapy (PRRT) with [177Lu]-DOTA-TATE is an effective treatment of neuroendocrine tumors (NETs). After each cycle of treatment, patient dosimetry evaluates the radiation dose to the risk organs, kidneys, and bone marrow, the most radiosensitive tissues. Absorbed doses are calculated from the radioactivity in ...
Published in BioNanoScience
The main purpose of the work is to study pharmacological peculiar properties of effect of pyrimidine derivatives, salt-like conjugates of the pyrimidine-based drug Xymedon (I) with biogenic acids (succinic (II), l-ascorbic (III), para-aminobenzoic (IV), niacin (V), and l-methionine (VI)) as well as a compound (VII), in which the atom N of the pyrim...
Published in Purinergic Signalling
Diabetes mellitus is characterized by increased levels of reactive oxygen species (ROS), leading to high levels of adenosine triphosphate (ATP) and the activation of purinergic receptors (P2X7), which results in cell death. Klotho was recently described as a modulator of oxidative stress and as having anti-apoptotic properties, among others. Howeve...
Published in Current Treatment Options in Pediatrics
PurposeThis paper will review the current roles of imaging for assessing the pediatric kidneys and urinary tract, while emphasizing recent trends and advances in imaging techniques.Recent findingsImaging aids in the diagnosis, assessment, and follow-up of the spectrum of congenital and developmental, infectious and inflammatory, traumatic, neoplast...
