Nakajima, Futoshi Nishimori, Hidefumi Hata, Fumitake Yasoshima, Takahiro Nomura, Hiroki Tanaka, Hiroshi Ohno, Keisuke Yanai, Yoshiyuki Kamiguchi, Kenjiro Sato, Noriyuki
...
Published in
Surgery Today
Purpose: Pancreatic cancer is associated with the poorest prognosis of any digestive cancer due to the high incidence of peritoneal dissemination, which is the cause of death in most cases. To determine the mechanisms of peritoneal dissemination in pancreatic cancer, we established a mouse model of high peritoneal dissemination. Methods: A novel hi...
Chandler, Nicole M. Canete, Jonathan J. Stuart, Keith E. Callery, Mark P.
Published in
Journal of Hepato-Biliary-Pancreatic Surgery
Despite advancements in the field of surgical oncology, the diagnosis of pancreatic cancer still carries a grave and dismal prognosis. Surgery alone for adenocarcinoma of the pancreatic head or uncinate process has a median survival time of 12 months. These grim statistics have led many to study the effects of combined multimodality therapy in the ...
Maosheng, Dong Ohtsuka, Takao Ohuchida, Jiro Inoue, Ken Yokohata, Kazunori Yamaguchi, Koji Chijiiwa, Kazuo Tanaka, Masao
Published in
Journal of Hepato-Biliary-Pancreatic Surgery
With the development of interventional radiology and endoscopy, the practice of inserting expandable metallic stents for malignant jaundice has become widespread. Many studies have compared surgical bypass with polyethylene stents, or metallic stents with polyethylene stents. However, few data are available on the comparison of surgical bypass and ...
Karademir, Sedat Sökmen, Selman Terzi, Cem Sağol, Özgül Özer, Erdener Astarcıoğlu, Hüseyin Çoker, Ahmet Astarcıoğlu, İbrahim
Published in
Journal of Hepato-Biliary-Pancreatic Surgery
The purpose of this study was to evaluate the role of angiogenesis, proliferative activity (assessed by Ki-67 expression), p53 and ras-oncogene (H-ras) expression, and conventional clinicopathologic factors in predicting overall survival rates in patients with pancreatic ductal adenocarcinoma. We followed-up 22 patients with ductal adenocarcinoma o...
Kikutsuji, Toru Harada, Masamitsu Tashiro, Seiki Ii, Setsuko Moritani, Maki Yamaoka, Takashi Itakura, Mitsuo
Published in
Journal of Hepato-Biliary-Pancreatic Surgery
The antiproliferative effects of somatostatin and its analogs on human pancreatic cancers were studied: (1) by evaluating the gene expression of somatostatin receptor (sstr) subtypes in human pancreatic cancer cell lines and cancer tissue specimens, (2) by evaluating the antiproliferative effects of somatostatin analogs, and (3) by evaluating the e...
Ohmura, Y. Kashiwa, T.
Published in
International Journal of Clinical Oncology
We report a case of pancreatic adenocarcinoma coexisting with a pancreatic pseudocyst, which showed gradual disappearance during preoperative examinations. The patient, an 83-year-old woman, had upper abdominal and back pain, and abdominal computed tomography (CT), on December 6, 1997, revealed an 11.0 ≧ 5.8 cm cystic mass in the pancreas. On Decem...
Matsuno, S. Egawa, S. Shibuya, K. Shimamura, H. Sunamura, M. Takeda, K. Katoh, H. Okada, S. Suda, K. Nakao, A.
...
Published in
International Journal of Clinical Oncology
Background. The Japanese Pancreas Society Registry Committee obtained data on 16 071 patients with pancrea-tic cancer diagnosed from 1981 to 1996. This is the largest multi-institutional retrospective study of the Japanese experience to describe the extent of disease and survival. Methods. Data were summarized according to age and sex and location ...
Yamamoto, M.
Published in
International Journal of Clinical Oncology
Okada, S.
Published in
International Journal of Clinical Oncology
Although pancreatic cancer (PC) continues to be a formidable disease, numerous treatment strategies are evolving and it is hoped that these will result in improved patient survival. Only surgical resection offers the opportunity for cure, but the prognosis of resected patients remains unfavorable because of postoperative recurrence. Accordingly, to...
Staib, L. Link, Karl Heinz Beger, Hans Günther
Published in
Langenbeck's Archives of Surgery
Background: In pancreatic cancer, multimodal protocols, involving chemotherapy, radiation, or regional treatment, are initiated to improve oncological outcome. Since pancreatic adenocarcinoma has been shown to be susceptible to immune stimulation, several immunotherapy approaches have been investigated to define the role of immunotherapy in pancrea...
