Liu, Huan Huang, Jingwei Liu, Hui Li, Feng Peng, Quansheng Liu, Chunhong
Published in
Chemical and Biological Technologies in Agriculture
BackgroundThe ketogenic diet (KD) can promote the anti-inflammatory metabolic state and increase ketone body level in rats. This study was to explore the effects and differences of KD with or without medium-chain fatty acids (MCFAs) on serum inflammatory factors and mTOR pathway in Sprague–Dawley (SD) rats.ResultsMale SD rats were assigned to five ...
Sondhi, Vishal Sharma, Suvasini
Published in
Indian journal of pediatrics
Nearly 20-40% of patients with epilepsy are likely to have drug resistant epilepsy (DRE). Add-on antiseizure drugs do not produce optimal seizure control in these patients. Among the non-pharmacological options, only resective surgery is curative. However, a large majority of patients are not candidates for resective epilepsy surgery. For these chi...
Mueller, Michael Ganesh, Ravindra Bonnes, Sara
Published in
Current nutrition reports
Depression and mood disorders impact a significant number of our population. The purpose of this review was to investigate the current literature on dietary strategies or supplements that may impact mood and cognition. Several recent studies and reviews have found that promoting a "healthy" diet may help improve depressive symptoms, and that such i...
Plotti, Francesco Terranova, Corrado Luvero, Daniela Bartolone, Martina Messina, Giuseppe Feole, Laura Cianci, Stefano Scaletta, Giuseppe Marchetti, Claudia Di Donato, Violante
...
Published in
Chemotherapy
Introduction: Diet may influence various aspects of human health. In fact, it is well known that diet can favour or not the development of various human pathologies, like diabetes, hypertension, and hypercholesterolaemia. Interestingly, diet has an influence in cancer development too (e.g., this relation has been studied for pancreatic, colonic, ga...
Klein, Pavel Tyrlikova, Ivana Zuccoli, Giulio Tyrlik, Adam Maroon, Joseph C.
Published in
Cancer & Metabolism
IntroductionGlioblastoma (GBM) has poor survival with standard treatment. Experimental data suggest potential for metabolic treatment with low carbohydrate ketogenic diet (KD). Few human studies of KD in GBM have been done, limited by difficulty and variability of the diet, compliance, and feasibility issues. We have developed a novel KD approach o...
Semprino, Marcos Fasulo, Lorena Fortini, Sebastian Martorell Molina, Catalina Isabel González, Lara Ramos, Paola Alejandra Martínez, Carolina Caraballo, Roberto
Published in
Epilepsy & behavior : E&B
The purpose of this study was to assess parent satisfaction with the management of ketogenic diet therapies (KDTs) through telemedicine using WhatsApp as the main tool. Parent satisfaction was longitudinally evaluated through questionnaires. The survey was developed with Google Questionnaire forms and sent via WhatsApp. The questionnaire consisted ...
Bosma, Karin J Rahim, Mohsin Oeser, James K McGuinness, Owen P Young, Jamey D O'Brien, Richard M
Published in
Molecular metabolism
G6PC2 is predominantly expressed in pancreatic islet beta cells. G6PC2 hydrolyzes glucose-6-phosphate to glucose and inorganic phosphate, thereby creating a futile substrate cycle that opposes the action of glucokinase. This substrate cycle determines the sensitivity of glucose-stimulated insulin secretion to glucose and hence regulates fasting blo...
Kong, Ganggang Liu, Junhao Li, Rong Lin, Junyu Huang, Zucheng Yang, Zhou Wu, Xiuhua Huang, Zhiping Zhu, Qingan Wu, Xiaoliang
...
Published in
Neurochemical research
Ketogenic diet (KD) has been shown to be beneficial in a range of neurological disorders, with ketone metabolite β-hydroxybutyrate (βOHB) reported to block the nucleotide oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome in bone marrow-derived macrophages. In this study, we show that pretreatment with KD or...
You, Yuehua Guo, Yongzheng Jia, Ping Zhuang, Biaobiao Cheng, Yu Deng, Hongpei Wang, Xiaowen Zhang, Cheng Luo, Suxin Huang, Bi
...
Published in
Nutrition & Metabolism
BackgroundKetogenic diet (KD) has been proposed to be an effective lifestyle intervention in metabolic syndrome. However, the effects of KD on cardiac remodeling have not been investigated. Our aim was to investigate the effects and the underling mechanisms of KD on cardiac remodeling in spontaneously hypertensive rats (SHRs).Methods10-week-old spo...
Wang, Yan-Qiu Fang, Zhi-Xu Zhang, Yi-Wei Xie, Ling-Ling Jiang, Li
Published in
Seizure
Dravet syndrome is an infantile epilepsy syndrome with drug resistant seizures and cognitive impairment. The aim of this meta-analysis was to summarize the findings of relevant published studies to identify the efficacy of a ketogenic diet in patients with Dravet syndrome and their compliance thereof, and to provide useful information for clinical ...
