Bose, Sohini Nguyen, Hieu D Ngo, Anh H Do, Loi H
Published in
Journal of inorganic biochemistry
In this work, we report on the development of fluorescent half-sandwich iridium complexes using a fluorophore attachment strategy. These constructs consist of pentamethylcyclopentadienyl (Cp*) iridium units ligated by picolinamidate donors conjugated to green-emitting boron-dipyrromethene (bodipy) dyes. Reaction studies in H2O/THF mixtures showed t...
Hidalgo, Nereida Moreno, Juan José García-Rubio, Inés Campos, Jesús
Published in
Angewandte Chemie (International ed. in English)
The organometallic chemistry of 4d and 5d transition metals has been vastly dominated by closed-shell states. The reactivity of their metalloradical species is though remarkable, albeit yet poorly understood and with limited mechanistic investigations available. In this work we report the synthesis and characterization of two mononuclear IrII speci...
Masada, Koichiro Kusumoto, Shuhei Nozaki, Kyoko
Published in
Angewandte Chemie (International ed. in English)
Herein, we report a novel method for the synthesis of metallabenzenes by swapping the phosphorus atom in an aromatic phosphinine ring with transition metal fragments. The oxidation of a phosphine-phosphinine-phosphine pincer iridium complex by O2 triggered the replacement of the phosphorus atom of the phosphinine ring by an iridium fragment to affo...
Jouffroy, Matthieu Nguyen, Thi-Mo Cordier, Marie Blot, Marielle Roisnel, Thierry Gramage-Doria, Rafael
Direct reductive amination (DRA) is a ubiquitous reaction in organic chemistry. This transformation between a carbonyl group and an amine is most often achieved using super stoichiometric amount of hazardous hydride reagents, thus being incompatible with many sensitive functional groups. DRA could also be achieved by means of chemo- or bio-catalysi...
Kuang, Shi Wei, Fangmian Karges, Johannes Ke, Libing Xiong, Kai Liao, Xinxing Ji, Liangnian Chao, Hui Gasser, Gilles
Despite the clinical success of photodynamic therapy (PDT), the application of this medical technique is intrinsically limited by the low oxygen concentrations found in cancer tumors which are hampering the production of the therapeutically necessary singlet oxygen (1 O2). To overcome this limitation, we report on a novel mitochondria-localized iri...
Durin, Gabriel Fontaine, Albane Berthet, Jean-Claude Nicolas, Emmanuel Thuéry, Pierre Cantat, Thibault
The metal-free catalytic hydrogenolysis of silyl triflates and halides (I, Br) to hydrosilanes is unlocked by using arylborane Lewis acids as catalysts. In the presence of a nitrogen base, the catalyst acts as a Frustrated Lewis Pair (FLP) able to split H2 and generate a boron hydride intermediate prone to reduce (pseudo)halosilanes. This metal-fre...
Bonfiglio, Anna
Different classes of N-heterocyclic carbene (NHC)-based ligands were explored for the preparation and investigation of novel families of emitters, based on Ir(III) and Re(I) metal complexes. Four novel tricarbonyl rhenium(I) complexes, where Re1 and Re2 are neutral and Re3 and Re4 are cationic, were explored as photocatalytic system for PEG-diacryl...
Duran Amaya, Silvia Alejandra
Diversifying energy sources by incorporating cleaner technologies i.e., renewable energy sources, are expected to play an important role to move from the current non-renewable dominated energy system. One of the promising energy carriers for renewable energy systems is hydrogen, and proton exchange membrane water electrolyzer (PEMWE) is one of the ...
Huang, Jing Liu, Zhennan Bloomer, Brandon J Clark, Douglas S Mukhopadhyay, Aindrila Keasling, Jay D Hartwig, John F
Synthetic biology enables microbial hosts to produce complex molecules from organisms that are rare or difficult to cultivate, but the structures of these molecules are limited to those formed by reactions of natural enzymes. The integration of artificial metalloenzymes (ArMs) that catalyse unnatural reactions into metabolic networks could broaden ...
Nishimura, Takahiro
Published in
Chemical record (New York, N.Y.)
Hydroarylation reactions via C-H activation, which compensate for shortcomings of classical methods based on the Friedel-Crafts reaction, is one of the most attractive methods to synthesize substituted arenes. This Personal Account reviews our recent studies on iridium-catalyzed intermolecular hydroarylation of vinyl ethers, alkynes, bicycloalkenes...