Tomassen, Monic M.M. Govers, Coen Vos, A.P. de Wit, Nicole J.W.
Background: There is increasing evidence that dietary fat, especially saturated fat, promotes the translocation of lipopolysaccharide (LPS) via chylomicron production in the gut. Chylomicrons can subsequently transport LPS to other parts of the body, where they can induce low-grade chronic inflammation that is linked to various metabolic and gut-re...
Xiao, Peng Liu, Xuan Zhang, He Li, Wenhua
Published in
Environmental pollution (Barking, Essex : 1987)
The intestine is a vital organ involved in chemical and nutrient uptake and biotransformation. Intestinal dysfunction can impair energy and material supply for reproduction. Isoflucypram, a new succinate dehydrogenase inhibitor fungicide, is highly toxic to aquatic systems. However, the chronic toxic effects of isoflucypram on intestinal differenti...
Evcan, Ezgi Gulec, Sukru
Published in
Genes & nutrition
Intestinal copper transporter (Atp7a) mutant-brindled mice with systemic Cu deficiency had elevated Cu levels in enterocyte cells without any perturbation of iron-regulating genes, suggesting that blood Cu level might be important for intestinal iron homeostasis during iron deficiency (ID). We hypothesized that the blood Cu level and polarization (...
Su, Huanhuan Li, Yaya Ma, Dongmei Fan, Jiajia Zhong, Zaixuan Zhu, Huaping
Published in
Comparative biochemistry and physiology. Part D, Genomics & proteomics
Multiple abiotic stresses are imposed on fish as a result of unprecedented changes in temperature and precipitation patterns in recent decades. It is unclear how teleosts respond to severe ambient salinity, alkalinity, and saline-alkalinity in terms of their metabolic and molecular osmoregulation processes. The metabolic reactions in the intestine ...
Wang, Weiwei Zheng, Dawen Zhang, Zhenzhen Ye, Hui Cao, Qingyun Zhang, Changming Dong, Zemin Feng, Dingyuan Zuo, Jianjun
Published in
Animal bioscience
This study was aimed to explore the efficacy of combination of endo-xylanase (Xyn) and xylan-debranching enzymes (arabinofuranosidase, Afd and feruloyl esterase, FE) in improving utilization of bran in piglet diet. In vitro experiments were firstly conducted to examine the enzymological properties of Xyn, Afd, and FE, concurrent with their effect o...
Metayer-Coustard, Sonia Rossignol, Christelle Blanc, Fany Lallier, Nathalie Schouler, Catherine Lantier, Frédéric Le Bihan-Duval, Elisabeth Travel, Angélique Lalmanach, Anne-Christine
Poultry production is an important agricultural sector for human food worldwide. Chicks after hatch often face health problems leading to economical losses that are deleterious for breeders. Avian β-defensin 2 (AvBD2) is a prominent host defense peptide of the intestinal mucosa of caecum and is involved in the resistance of poultry to bacterial pat...
Liu, Wei Lim, Kah-Leong Tan, Eng-King
Published in
Translational neurodegeneration
Aberrant aggregation of α-synuclein (α-syn) is a key pathological feature of Parkinson's disease (PD), but the precise role of intestinal α-syn in the progression of PD is unclear. In a number of genetic Drosophila models of PD, α-syn was frequently ectopically expressed in the neural system to investigate the pathobiology. We investigated the pote...
Arnone, Djésia Chabot, Caroline Heba, Anne-Charlotte Kökten, Tunay Caron, Bénédicte Hansmannel, Franck Dreumont, Natacha Ananthakrishnan, Ashwin N Quilliot, Didier Peyrin-Biroulet, Laurent
...
Published in
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Sugar overconsumption is linked to a rise in the incidence of noncommunicable diseases such as diabetes, cardiovascular diseases, and cancer. This increased incidence is becoming a real public health problem that is more severe than infectious diseases, contributing to 35 million deaths annually. Excessive intake of free sugars can cause many of th...
Syed-Abdul, Majid M Stahel, Priska Tian, Lili Xiao, Changting Nahmias, Avital Lewis, Gary F
Published in
Biochimica et biophysica acta. Molecular and cell biology of lipids
Dietary triglycerides (TG) retained in the intestine after a meal can be mobilized many hours later by glucagon-like peptide-2 (GLP-2) in humans and animal models, despite the well-documented absence of expression of the GLP-2 receptor on enterocytes. In this study, we examined the site of GLP-2 action to mobilize intestinal lipids and enhance chyl...
Breves, Jason P Puterbaugh, Katie M Bradley, Serena E Hageman, Annie E Verspyck, Adrian J Shaw, Lydia H Danielson, Elizabeth C Hou, Yubo
Published in
General and comparative endocrinology
Prolactin (Prl) was identified over 60 years ago in mummichogs (Fundulus heteroclitus) as a "freshwater (FW)-adapting hormone", yet the cellular and molecular targets of Prl in this model teleost have remained unknown. Here, we conducted a phylogenetic analysis of two mummichog Prl receptors (Prlrs), designated Prlra and Prlrb, prior to describing ...