Ceridono, Mara Chasserot-Golaz, Sylvette Vitale, Nicolas Gasman, Stéphane Ory, Stéphane
Published in
Methods in molecular biology (Clifton, N.J.)
Plasma membrane proteins are amenable to endocytosis assays since they are easily labeled by reagents applied in the extracellular medium. This has been widely exploited to study constitutive endocytosis or ligand-induced receptor endocytosis. Compensatory endocytosis is the mechanism by which components of secretory vesicles are retrieved after ve...
Rodgers, Rachel F; Fuller-Tyszkiewicz, Matthew; Markey, Charlotte; Granero-Gallegos, Antonio; Sicilia, Alvaro; Caltabiano, Marie; Blackburns, Marie-Eve; Hayami-Chisuwa, Naomi; Strodl, Esben; Aimé, Annie;
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The aim of the current study was to examine the psychometric properties of two well-established measures of sociocultural influence and internalization of the thin/low body fat ideal and muscular ideal. Data from 6272 emerging adults (68.9 % female), aged 18-30 years from Australia, Belgium, Canada, China, Italy, Japan, Spain, and the U.S. were inc...
Rodgers, Rachel F. Fuller-Tyszkiewicz, Matthew Markey, Charlotte Granero-Gallegos, Antonio Sicilia, Alvaro Caltabiano, Marie Blackburns, Marie Eve Hayami-Chisuwa, Naomi Strodl, Esben Aimé, Annie
...
The aim of the current study was to examine the psychometric properties of two well-established measures of sociocultural influence and internalization of the thin/low body fat ideal and muscular ideal. Data from 6272 emerging adults (68.9 % female), aged 18–30 years from Australia, Belgium, Canada, China, Italy, Japan, Spain, and the U.S. were inc...
Camacho, Elise Marie, Nicolas Dupas, Quentin Martel, Caroline Nowoczyn, Marie Elie, Nicolas Rochais, Christophe Tóth, Géza Allouche, Stéphane
International audience
Schlesier, Tim Siegmund, Anke Rescher, Ursula Heilmann, Christine
Published in
International journal of medical microbiology : IJMM
Staphylococcus aureus internalization by non-professional phagocytes is considered a main pathogenicity mechanism leading to chronic infections. The well-established mechanism of Staphylococcus aureus internalization is mediated by fibronectin (Fn)-binding proteins (FnBPs), Fn as a bridging molecule and the host cell α5β1 integrin. We previously id...
Imaizumi, Takamichi Otsubo, Shigeki Komai, Masato Takada, Hidenori Maemoto, Michihiro Kobayashi, Atsuko Otsubo, Nobumasa
Published in
Bioorganic & medicinal chemistry
We previously reported 2-aminobenzoxazole analogue 1 as a potent ChemR23 inhibitor. The compound showed inhibitory activity against chemerin-induced calcium signaling through ChemR23 internalization in CAL-1 cells, which are cell lines of plasmacytoid dendric cells (pDCs). Furthermore, compound 2 inhibited chemotaxis of CAL-1 triggered by chemerin ...
Chen, Jing Chen, Xiaoyu Li, Sheng Jiang, Yunlu Mao, Huiling Zhang, Rumin Ji, Bingyuan Yan, Maocai Cai, Xin Wang, Chunmei
...
Published in
Redox biology
The apelin and Elabela proteins constitute a spatiotemporal double-ligand system that controls apelin receptor (APJ) signal transduction. Phosphorylation of multiple sites within the C-terminus of APJ is essential for the recruitment of β-arrestins. We sought to determine the precise mechanisms by which apelin and Elabela promote APJ phosphorylatio...
Ogunlade, Blessing Guidry, Jessie J Mukerjee, Snigdha Sriramula, Srinivas Lazartigues, Eric Filipeanu, Catalin M
Published in
Cellular and molecular neurobiology
We have previously shown that angiotensin-converting enzyme 2 (ACE2), an enzyme counterbalancing the deleterious effects of angiotensin type 1 receptor activation by production of vasodilatory peptides Angiotensin (Ang)-(1-9) and Ang-(1-7), is internalized and degraded in lysosomes following chronic Ang-II treatment. However, the molecular mechanis...
Nonaka, Saori Nakanishi, Hiroshi
Published in
Neurochemistry international
Much attention has been paid to the connection between periodontitis and Alzheimer's disease (AD). We previously showed that infection of P. gingivalis, one of major periodontal pathogen causing periodontitis, induced migration and inflammatory responses in murine microglia through gingipain-induced activation of protease-activated receptor 2 (PAR2...
Madani, Mansure Vedadhir, AbouAli Larijani, Bagher Khazaei, Zahra Gharamaleki, Ahad Faramarz
Published in
Science and engineering ethics
Physicians try hard to alleviate mental and physical ailments of their patients. Thus, they are heavily burdened by observing ethics and staying well-informed while improving health of their patients. A major ethical concern or dilemma in medication is that some physicians know their behavior is unethical, yet act against their moral compass. This ...