Biostatistics (Oxford, England)
Individuals often respond differently to identical treatments, and characterizing such variability in treatment response is an important aim in the practice of personalized medicine. In this article, we describe a nonparametric accelerated failure time model that can be used to analyze heterogeneous treatment effects (HTE) when patient outcomes are...
BackgroundLDL cholesterol (LDL-C) concentration is modified by dietary and genetic factors; however, little is known about the details of this relationship. Our aim was to investigate the associations taking into account dietary assessment methods, seasonal effects and missing values.MethodsStudy subjects completed food frequency questionnaires (FF...
Research in developmental disabilities
Both siblings and parents are important interactional partners for children with ASD, but we know little about whether these interactions differ between these two groups, or between older and younger siblings. To gather data about how parents perceive the interactional behaviors displayed by their child with ASD in play with their typically develop...
Interdisciplinary sciences, computational life sciences
Non-coding RNA (ncRNA) plays an important role in regulating biological activities of animals and plants, and the representative ones are microRNA (miRNA) and long non-coding RNA (lncRNA). Recent research has found that predicting the interaction between miRNA and lncRNA is the primary task for elucidating their functional mechanisms. Due to the sm...
Biochemical and biophysical research communications
As a scaffold protein, Receptor for Activated C Kinase 1a (RACK1) interacts with many proteins and is involved in multiple biological processes in Arabidopsis. However, the global RACK1 protein interaction network in higher plants remains poorly understood. Here, we generated a yeast two-hybrid library using mixed samples from different development...
Clinica chimica acta; international journal of clinical chemistry
To evaluate the interaction effects between lipoprotein (a) (Lp(a)) and low-density lipoprotein cholesterol (LDL-C) on first incident acute myocardial infarction (AMI) among Chinese Han population. 1522 cases and 1691 controls were retrospectively analyzed. All subjects were grouped by Lp(a) or LDL-C level. Compared with reference group (LDL-C
Design for Interaction
Environmental Health and Preventive Medicine
BackgroundMaintenance of instrumental activities of daily living (IADL) and social role (SR) is crucial to keep independent life because the decline in SR and IADL was a significant predictor of dependence in basic ADL in later. The independent effect of physical and cultural leisure activities and their effect modification on the IADL remains unkn...
Environmental pollution (Barking, Essex : 1987)
The wide application of bisphenol A (BPA) leads to the emergence of BPA residuals in natural water environments. Dissolved organic matter (DOM) existed in water can bind with BPA, hence influencing the migration and transformation of BPA in aquatic environments. pH is a crucial factor governing the binding interactions between DOM and BPA. However,...
As a new kind of solvent and catalyst, the functionalized ionic liquids (ILs) had been successfully used in the conversion of fructose to high value-added biofuels. In this work, a detailed density functional theory (DFT) calculation had been carried out to investigate the interactions of fructose-ILs system. To study the effect of different anions...