Irahal, Imane Nait Guenaou, Ismail Lahlou, Fatima Azzahra Hmimid, Fouzia Bourhim, Noureddine
Published in
Hormones (Athens, Greece)
This study aimed to evaluate the antioxidant and antidiabetic properties of clove essential oil (CEO) and to elucidate its mode of action, using selected biochemical targets, relevant to diabetes, and, specifically, its inhibitory effect on the polyol pathway. In the current study, CEO was examined for its inhibitory effects on aldose reductase in ...
Mayhew, Stephen D Coleman, Sebastian C Mullinger, Karen J Can, Cam
Published in
NeuroImage
Ipsilateral sensorimotor (iSM1) cortex negative BOLD responses (NBR) are observed to unilateral tasks and are thought to reflect a functionally relevant component of sensorimotor inhibition. Evidence suggests that sensorimotor inhibitory mechanisms degrade with age, along with aspects of motor ability and dexterity. However, understanding of age-re...
He, Jason L Hirst, Rebecca J Puri, Rohan Coxon, James Byblow, Winston Hinder, Mark Skippen, Patrick Matzke, Dora Heathcote, Andrew Wadsley, Corey G
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Published in
Behavior research methods
The stop-signal paradigm has become ubiquitous in investigations of inhibitory control. Tasks inspired by the paradigm, referred to as stop-signal tasks, require participants to make responses on go trials and to inhibit those responses when presented with a stop-signal on stop trials. Currently, the most popular version of the stop-signal task is ...
Monk, R. L. Qureshi, A. Wernham, G. Heim, D.
Published in
Psychopharmacology
Background It is well known that, owing to associative processing, olfactory cues can impact memory, emotion and behaviour. Research also points to a link between the smells of particular substances and craving. Yet, to date, little research has investigated how smell may impact other cognitive processes that are known to drive alcohol consumption....
Akinbomi, Julius G. Patinvoh, Regina J. Taherzadeh, Mohammad J.
Published in
Biotechnology for Biofuels and Bioproducts
The attention that high solids anaerobic digestion process (HS-AD) has received over the years, as a waste management and energy recovery process when compared to low solids anaerobic digestion process, can be attributed to its associated benefits including water conservation and smaller digester foot print. However, high solid content of the feeds...
Kellock, Miriam Rahikainen, Jenni Borisova, Anna S. Voutilainen, Sanni Koivula, Anu Kruus, Kristiina Marjamaa, Kaisa
Published in
Biotechnology for Biofuels and Bioproducts
Background Enzymatic hydrolysis of lignocellulosic biomass into platform sugars can be enhanced by the addition of accessory enzymes, such as xylanases. Lignin from steam pretreated biomasses is known to inhibit enzymes by non-productively binding enzymes and limiting access to cellulose. The effect of enzymatically isolated lignin on the hydrolysi...
Pan, Xiaoli Pei, Junping Wang, Aoxue Shuai, Wen Feng, Lu Bu, Faqian Zhu, Yumeng Zhang, Lan Wang, Guan Ouyang, Liang
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Published in
Acta pharmaceutica Sinica. B
The mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway is widely activated by a variety of extracellular stimuli, and its dysregulation is associated with the proliferation, invasion, and migration of cancer cells. ERK1/2 is located at the distal end of this pathway and rarely undergoes muta...
Pang, Xiaoyan Tang, Chongzhuang Guo, Runcong Chen, Xiaoyan
Published in
Pharmacology & therapeutics
Oxidative metabolism is one of the major biotransformation reactions that regulates the exposure of xenobiotics and their metabolites in the circulatory system and local tissues and organs, and influences their efficacy and toxicity. Although cytochrome (CY)P450s play critical roles in the oxidative reaction, extensive CYP450-independent oxidative ...
Long, Samuel Berkemeier, Brian
Published in
Methods (San Diego, Calif.)
Sensitive detection of viral nucleic acids is critically important for diagnosis and monitoring of the progression of infectious diseases such as those caused by SARS-CoV2, HIV-1, and other viruses. In HIV-1 infection cases, assessing the efficacy of treatment interventions that are superimposed on combination antiretroviral therapy (cART) has bene...
Thakur, Abhinay Sharma, Shveta Ganjoo, Richika Assad, Humira Kumar, Ashish
Published in
Journal of Physics: Conference Series
Over the past decade, green chemistry has been emphasizing the importance of environmental sustainability and human health, aiming to minimize toxins and reducing wastes in an economically beneficial manner. The field of metallic materials deterioration, generally faced by the utilization of toxic compounds, discovered a promising research field in...
