Al-Jassas, Hawraa Kadhem Al-Hakeim, Hussein Kadhem Maes, Michael
Published in
Journal of affective disorders
COVID-19 is associated with neuropsychiatric symptoms including increased depressive, anxiety and chronic fatigue-syndrome (CFS)-like and physiosomatic symptoms. To delineate the associations between affective and CFS-like symptoms in COVID-19 and chest computed tomography scan anomalies (CCTAs), oxygen saturation (SpO2), interleukin (IL)-6, IL-10,...
Jain, Siddhi Durugkar, Sneha Saha, Pritam Gokhale, Sharad B Naidu, V G M Sharma, Pawan
Published in
European journal of pharmacology
Airflow limitation in chronic obstructive pulmonary disease (COPD) is the result of exaggerated airway fibrosis and obliteration of the small airways due to persistent inflammation, and an impaired anti-oxidant response. EMT has been implicated as an active signalling process in cigarette smoke (CS)-induced lung pathology, and macrolide Azithromyci...
Om, Prakash Gopinath, M S Madan Kumar, P Muthu Kumar, S P Kudachikar, V B
Published in
Journal of ethnopharmacology
Pyrus pashia Buch ham ex. D. Don (Kainth) fruit from the Himalayan region is traditionally consumed by native people in the form of decoctions for various clinical conditions including inflammatory diseases. However, scientific studies on the biofunctional properties of Kainth fruits are still scarce. The study is aimed to investigate the anti-infl...
Murakami, Shigeru Hirazawa, Chihiro Yoshikawa, Rina Mizutani, Toshiki Ohya, Takuma Ma, Ning Ikemori, Takahiko Ito, Takashi Matsuzaki, Chiaki
Published in
Nutrition & Metabolism
BackgroundThe obesity epidemic has become a serious public health problem in many countries worldwide. Seaweed has few calories and is rich in active nutritional components necessary for health promotion and disease prevention. The aim of this study was to investigate the effects of the Campylaephora hypnaeoides J. Agardh (C. hypnaeoides), an edibl...
Hannemann, Carmen Schecker, Johannes H Brettschneider, Alica Grune, Jana Rösener, Nicole Weller, Andrea Stangl, Verena Fisher, Edward A Stangl, Karl Ludwig, Antje
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Published in
Cardiovascular research
Atherosclerosis is a chronic inflammatory disease of the arterial vessel wall and anti-inflammatory treatment strategies are currently pursued to lower cardiovascular disease burden. Modulation of recently discovered inactive rhomboid protein 2 (iRhom2) attenuates shedding of tumour necrosis factor-alpha (TNF-α) selectively from immune cells. The p...
Xiao, Qian Qian, Jingyi Evans, Daniel S Redline, Susan Lane, Nancy E Ancoli-Israel, Sonia Scheer, Frank A J L Stone, Katie
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Chronic increases in pro-inflammatory cytokines in older adults, known as inflammaging, are an important risk factor for morbidity and mortality in the aging population. It has been suggested that circadian disruption may play a role in chronic inflammation, but there has been limited study that investigated the overall profile of 24-hour rest-acti...
Claudia, Goettsch Agnieszka, Strzelecka-Kiliszek Laurence, Bessueille Thibaut, Quillard Laura, Mechtouff Slawomir, Pikula Emmanuelle, Canet-Soulas Millan, Jose Luis Caroline, Fonta David, Magne
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Published in
Cardiovascular research
Cardiovascular calcification (CVC) is associated with increased morbidity and mortality. It develops in several diseases and locations, such as in the tunica intima in atherosclerosis plaques, in the tunica media in type 2 diabetes and chronic kidney disease, and in aortic valves. In spite of the wide occurrence of CVC and its detrimental effects o...
Dehghani, Tima Thai, Phung N Sodhi, Harkanwalpreet Ren, Lu Sirish, Padmini Nader, Carol E Timofeyev, Valeriy Overton, James L Li, Xiaocen Lam, Kit S
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Published in
Cardiovascular research
One of the hallmarks of myocardial infarction (MI) is excessive inflammation. During an inflammatory insult, damaged endothelial cells shed their glycocalyx, a carbohydrate-rich layer on the cell surface which provides a regulatory interface to immune cell adhesion. Selectin-mediated neutrophilia occurs as a result of endothelial injury and inflamm...
Bertero, Edoardo Dudek, Jan Cochain, Clement Delgobo, Murilo Ramos, Gustavo Gerull, Brenda Higuchi, Takahiro Vaeth, Martin Zernecke, Alma Frantz, Stefan
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Published in
Cardiovascular research
The interplay between the cardiovascular system, metabolism, and inflammation plays a central role in the pathophysiology of a wide spectrum of cardiovascular diseases, including heart failure. Here, we provide an overview of the fundamental aspects of the interrelation between inflammation and metabolism, ranging from the role of metabolism in imm...
Kieran, Nicholas W. Suresh, Rahul Dorion, Marie-France MacDonald, Adam Blain, Manon Wen, Dingke Fuh, Shih-Chieh Ryan, Fari Diaz, Roberto J. Stratton, Jo Anne
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Published in
Journal of Neuroinflammation
BackgroundAstrocytes are the most numerous glial cell type with important roles in maintaining homeostasis and responding to diseases in the brain. Astrocyte function is subject to modulation by microRNAs (miRs), which are short nucleotide strands that regulate protein expression in a post-transcriptional manner. Understanding the miR expression pr...
