Published in La Revue de medecine interne
Ischemic stroke accounts for 80% of overall stroke, and is one of the leading causes of death, disability and dementia in worldwide. Management of patients with acute ischemic stroke dramatically improved over time with the implementation of intensive care stroke units, the development of acute recanalization strategies, the optimization of the man...
Acute ischemic stroke is a major cause of death and disability and remains a major global health problem. Compliance with international recommendations is essential in the management of ischemic stroke during the acute phase in order to prevent early complications and recurrence. This study is the first in Lebanon to assess compliance with guidelin...
Introduction: Early management of patients with acute ischemic stroke (AIS) remains crucial. Efficacy of intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) is strongly time dependent. Door-to-needle time (DTN) is a powerful marker of in-hospital delays, with a benchmark ≤ 60 minutes currently recommended. Method: We studied the impact ...
Les étiologies cardio-emboliques représentent 30% des AIC et AIT. Leur prise en charge a été modifiée par plusieurs avancées récentes, notamment chez les patients les plus jeunes. Les recommandations européennes préconisent la réalisation d’une échographie cardiaque dans le bilan minimal de l’AIC.Objectif : Décrire la place de l’échographie cardiaq...
The current long-term prognosis after transient ischaemic attack (TIA) or ischaemic stroke is not well known. I aimed to determine the long-term absolute residual risks of recurrent stroke and coronary events after TIA or ischaemic stroke and identify individuals who remain at high absolute risk of recurrent ischaemic events despite current seconda...
Introduction. Trente pour cent des patients atteints d’AVC ischémique développent une dépression post-AVC (DPA), complication de mauvais pronostic et sous-diagnostiquée. L’inflammation liée à l’AVC rend compte d’une partie importante de la physiopathologie de la DPA. Les marqueurs inflammatoires de routine tels que la CRP (C-reactive protein), la f...
Published in Archives of cardiovascular diseases
Unlike previous randomized clinical trials (RCTs), recent trials and meta-analyses have shown that transcatheter closure of patent foramen ovale (PFO) reduces stroke recurrence risk in young and middle-aged adults with an otherwise unexplained PFO-associated ischaemic stroke. To produce an expert consensus on the role of transcatheter PFO closure a...
Background and Purpose: Aneurysmal subarachnoid hemorrhage (aSAH) is a serious disease with high rate of mortality and morbidity, especially because of the occurrence of delayed cerebral ischemia (DCI) related with cerebral vasospasm or not. Protein S100b, a glial protein, is a wellknownbiomarker of cerebral ischemia and high serum S100b level afte...
Introduction : l’hyperglycémie en phase aiguë d’un infarctus cérébral traité par thrombolyse ou thérapie combinée est associée à un mauvais pronostic fonctionnel, en majorant la croissance du cœur ischémique. Nous étudions le rôle délétère de l’hyperglycémie sur le pronostic fonctionnel en fonction de la pénombre ischémique et de la recanalisation....
Published in La Revue de medecine interne
Acute management of ischemic stroke is a burning topic in 2017 since stroke represents the leading cause of acquired handicap in adults. Over the last past years, major improvement took place, especially with the demonstration of the efficacy of mechanical thrombectomy, thus needing to better organize care pathways, and optimize access to neurologi...
