Smarius, Laetitia J C A Strieder, Thea G A Doreleijers, Theo A H Vrijkotte, Tanja G M Zafarmand, M Hadi de Rooij, Susanne R
Published in
European archives of psychiatry and clinical neuroscience
Genetic predisposition of social sensitivity might affect vulnerability to develop psychopathology after early life stress exposure. This study examined whether maternal verbally aggressive behavior in early infancy interacts with oxytocin polymorphisms in developing internalizing symptoms at ages 5-6 and 11-12. In the Amsterdam-Born-Children-and-t...
Kobayashi, Yoshiko Tokuda, Narumi Adachi, Sho Takeshima, Yasuhiro Hirose, Munetaka Shima, Masayuki Kamijima, Michihiro Yamazaki, Shin Ohya, Yukihiro Kishi, Reiko
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Published in
Environmental Health and Preventive Medicine
BackgroundThe neurotoxicity of general anesthesia to the developing human brains is controversial. We assessed the associations between surgery under general anesthesia in infancy and development at age 1 year using the Japan Environment and Children’s Study (JECS), a large-scale birth cohort study.MethodsIn the JECS, 103,062 pregnancies and 104,06...
Tong, Yongqing Liu, Bei Zheng, Hongyun Bao, Anyu Wu, Zegang Gu, Jian Tan, Bi-Hua McGrath, Mary Kane, Shriya Song, Chunhua
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Published in
BMC Medical Genetics
BackgroundGlucose-6-phosphate dehydrogenase deficiency (D-G6PD) is an X-linked recessive disorder resulted from deleterious variants in the housekeeping gene Glucose-6-phosphate 1-dehydrogenase (G6PD), causing impaired response to oxidizing agents. Screening for new variations of the gene helps with early diagnosis of D-G6PD resulting in a reductio...
Ogata, Tomomi Muramatsu, Kazuhiro Miyana, Kaori Ozawa, Hiroshi Iwasaki, Motoki Arakawa, Hirokazu
Published in
BMC Pediatrics
BackgroundCongenital central hypoventilation syndrome (CCHS) is a rare disease characterized by sleep apnea. Anoxia often occurs soon after birth, and it is important to prevent anoxia-mediated central nervous system complications; however, data on the relationship between respiratory management and the prognosis for intellectual development of pat...
Qian, Tian Zhu, Haitao Zhu, Li Chen, Chao Shen, Chun Zhang, Rong
Published in
BMC Gastroenterology
BackgroundStudies of microbiota composition of infants with small intestinal ostomy due to various etiologies are limited. Here, we characterized the intestinal microbiota of neonates with ileostomy resulting from distinct primary diseases.MethodsFifteen patients with necrotizing enterocolitis, eight patients with meconium peritonitis, and seven pa...
Murki, Srinivas Kandraju, Hemasree Oleti, Tejopratap Saikiran, Gaddam, Pramod
Published in
Indian journal of pediatrics
To identify risk factors and outcomes associated with early failure of nasal continuous positive airway pressure (CPAP) in premature infants with respiratory distress (RD). This is a retrospective observational study of all the preterm infants with RD primarily supported on nasal CPAP and included in CPAP trials conducted at the study site. Data wa...
Blauvelt, Christine A Chiu, Catherine Donovan, Anne L Prahl, Mary Shimotake, Thomas K George, Ronald B Schwartz, Brian S Farooqi, Naghma A Ali, Syed S Cassidy, Arianna
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BACKGROUND:Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by...
Matava, Clyde T Kovatsis, Pete G Lee, Jennifer K Castro, Pilar Denning, Simon Yu, Julie Park, Raymond Lockman, Justin L Von Ungern-Sternberg, Britta Sabato, Stefano
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The severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) pandemic has challenged medical systems and clinicians globally to unforeseen levels. Rapid spread of COVID-19 has forced clinicians to care for patients with a highly contagious disease without evidence-based guidelines. Using a virtual modified nominal group...
Whitley, Gregory Adam Hemingway, Pippa Law, Graham Richard Wilson, Caitlin Siriwardena, Aloysius Niroshan
Published in
The American journal of emergency medicine
We aimed to identify predictors of effective management of acute pain in children in the pre-hospital setting. A retrospective cross-sectional study using electronic clinical records from one large UK ambulance service during 01-Oct-2017 to 30-Sep-2018 was performed using multivariable logistic regression. We included all children
Tang, Jie Liu, Xiang Ma, Tongshen Lv, Xiaofeng Jiang, Weiwei Zhang, Jie Lu, Changgui Chen, Huan Li, Wei Li, Hongxing
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Published in
Clinical nutrition (Edinburgh, Scotland)
Various enhanced recovery after surgery (ERAS) guidelines have been established for several kinds of adult surgeries. While the guidelines for pediatric surgeries remained to be explored. The aim of the study was to prospectively evaluate the safety and efficacy of an ERAS protocol for Hirschsprung's disease (HSCR) infants undergoing pull-through p...
