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with Immunomodulatory potential as keyword
Abu-Shahba, Nourhan Mahmoud, Marwa Abdel-Rasheed, Mazen Darwish, Yasmine AbdelKhaliq, Ahmad Mohammed, Eman ElHefnawi, Mahmoud Azmy, Osama
Published in
Cell Regeneration
BackgroundAdipose-derived stem cells (ASCs) are considered ideal candidates for both research and cellular therapy due to ease of access, large yield, feasibility, and efficacy in preclinical and clinical studies. Unlike the subcutaneous abdominal fat depot, breast ASCs features are still not well recognized, limiting their possible therapeutic use...
Caselli, Gianfranco Bonazzi, Albino Lanza, Marco Ferrari, Flora Maggioni, Daniele Ferioli, Cristian Giambelli, Roberto Comi, Eleonora Zerbi, Silvia Perrella, Marco
...
Published in
Arthritis Research & Therapy
BackgroundProstaglandin E2 (PGE2) acts via its EP4 receptor as a cytokine amplifier (e.g., interleukin [IL]-6) and induces the differentiation and expansion of inflammatory T-helper (Th) lymphocytes. These mechanisms play a key role in the onset and progression of rheumatoid arthritis (RA). We present the pharmacological characterisation of CR6086,...
Maatouk, Mouna Mustapha, Nadia Mokdad-Bzeouich, Imen Chaaban, Hind Abed, Besma Iaonnou, Irina Ghedira, Kamel Ghoul, Mohamed Ghedira, Leila Chekir
Published in
Cell Stress and Chaperones
Phytochemicals extracted from flowers, roots and bark, leaves, and other plant sources have been used extensively throughout human history with varying levels of efficacy in prevention and treatment of disease. Recently, advanced methods for characterization and clinical use of these materials have allowed modern understanding of their properties t...
Bertolo, Alessandro Pavlicek, David Gemperli, Armin Baur, Martin Pötzel, Tobias Stoyanov, Jivko
Published in
Journal of stem cells & regenerative medicine
Immunomodulatory properties of mesenchymal stem cells (MSC) are key components of their successful applications in clinical setting. However, treatments based on MSC immunomodulation need understanding of cell characteristics before cell transplantation. We used live-imaging to test the suitability of the MSC motility as a parameter for quick predi...
