Activation of coagulation in chronic urticaria in relation to disease severity and activity
Published in Allergologia et Immunopathologia
Published in Allergologia et Immunopathologia
Published in The Journal of experimental medicine
Venoms frequently co-opt host immune responses, so study of their mode of action can provide insight into novel inflammatory pathways. Using bee and wasp venom responses as a model system, we investigated whether venoms contain CD1-presented antigens. Here, we show that venoms activate human T cells via CD1a proteins. Whereas CD1 proteins typically...
Published in Current Opinion in Immunology
IL-33 is a nuclear cytokine from the IL-1 family constitutively expressed in epithelial barrier tissues and lymphoid organs, which plays important roles in type-2 innate immunity and human asthma. Recent studies indicate that IL-33 induces production of large amounts of IL-5 and IL-13 by group 2 innate lymphoid cells (ILC2s), for initiation of alle...
Published in Pediatric Allergy, Immunology, and Pulmonology
Published in Eur J Immunol
Published in Journal of Neuroimmunology
Published in Journal of Allergy and Clinical Immunology
Published in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Published in The Journal of allergy and clinical immunology
Published in Journal of Vascular Research
Inflammation is a highly regulated process with common but also specific characteristics in each tissue affected. Recruitment of leukocytes from the blood to the injured tissue is an important early step in the inflammatory cascade. This review highlights the role of connexins (Cxs) in the regulation of both acute and chronic inflammatory processes...