Ferro, Matteo Lucarelli, Giuseppe de Cobelli, Ottavio Vartolomei, Mihai Dorin Damiano, Rocco Cantiello, Francesco Crocerossa, Fabio Perdonà, Sisto Del Prete, Paola Cordima, Giovanni
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Published in
World journal of urology
The association between circulating total testosterone (T) levels and clinically significant PCa is still a matter of debate. In this study, we evaluated whether serum testosterone levels may have a role in predicting unfavorable disease (UD) and biochemical recurrence (BCR) in patients with clinically localized (≤ cT2c) ISUP grade group 1 PCa at b...
Walton-Diaz, Annerleim Madariaga-Venegas, Manuel Aviles, Nicolas Roman, Juan Carlos Gallegos, Ivan Burotto, Mauricio
Published in
Current Urology Reports
Purpose of ReviewThe purpose of this review is to summarize the most current literature regarding the most important aspects to consider when developing a center of excellence for prostate imaging and biopsy.Recent FindingsMultiparametric MRI (mp-MRI) has changed the way we diagnose and treat prostate cancer. This imaging modality allows for more p...
Compérat, Eva M Burger, Maximilian Gontero, Paolo Mostafid, A Hugh Palou, Joan Rouprêt, Morgan van Rhijn, Bas W G Shariat, Shahrokh F Sylvester, Richard J Zigeuner, Richard
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Published in
European urology focus
In the management of urothelial carcinoma, determination of the pathological grade aims at stratifying tumours into different prognostic groups to allow evaluation of treatment results, and optimise patient management. This article reviews the principles behind different grading systems for urothelial bladder carcinoma discussing their reproducibil...
Zheng, Xiaonan Qiu, Shi Liao, Xinyang Han, Xin Jin, Kun Yang, Lu Wei, Qiang
Published in
OncoTargets and therapy
Objective To evaluate the association between metabolic syndrome (MetS) and the accumulation of its components with prostate cancer (PCa). Patients and methods Patients undergoing radical prostatectomy were retrospectively included. Patients were grouped by low risk and intermediate-high risk according to International Society of Urological Patholo...
Neuzillet, Yann Raynaud, Jean-Pierre Dreyfus, Jean-François Radulescu, Camélia Rouanne, Mathieu Schneider, Marc Krish, Sylvie Rouprêt, Morgan Drouin, Sarah J. Comperat, Eva
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Published in
Hormones and Cancer
Failure rates after first-line treatment of localized prostate cancer (PCa) treatment remain high. Improvements to patient selection and identification of at-risk patients are central to reducing mortality. We aimed to determine if cancer aggressiveness correlates with androgen levels in patients undergoing radical prostatectomy for localized PCa. ...
Egevad, Lars Delahunt, Brett Berney, Daniel M Bostwick, David G Cheville, John Comperat, Eva Evans, Andrew J Fine, Samson W Grignon, David J Humphrey, Peter A
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Published in
Histopathology
Despite efforts to standardise grading of prostate cancer, even among experts there is still a considerable variation in grading practices. In this study we describe the use of Pathology Imagebase, a novel reference image library, for setting an international standard in prostate cancer grading. The International Society of Urological Pathology (IS...
Idrees, Muhammad T Ulbright, Thomas M Oliva, Esther Young, Robert H Montironi, Rodolfo Egevad, Lars Berney, Daniel Srigley, John R Epstein, Jonathan I Tickoo, Satish K
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Published in
Histopathology
The World Health Organization (WHO) released a new tumour classification for the genitourinary system in early 2016 after consensus by pathologists with expertise in these organs. It utilized the framework of the 2004 classification, and incorporated the most up-to-date information concerning these tumours. In testicular tumours, the majority of th...
Loeb, Stacy Folkvaljon, Yasin Robinson, David Lissbrant, Ingela Franck Egevad, Lars Stattin, Pär
Published in
European urology
The new Gleason grade groups, ranging from 1-5, provide a simplified, user-friendly classification system to predict the risk of recurrence after prostatectomy and radiation therapy.
Loeb, Stacy Folkvaljon, Yasin Robinson, David Lissbrant, Ingela Franck Egevad, Lars Stattin, Pär
Published in
European urology
The new Gleason grade groups, ranging from 1-5, provide a simplified, user-friendly classification system to predict the risk of recurrence after prostatectomy and radiation therapy.
Rioux-Leclercq, Nathalie Ferran, Algaba Mahul, Amin Argani, Pedram Billis, Athanase Bonsib, Stephen Cheng, Liang Cheville, John Eble, John Egevad, Lars
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Published in
Annales de pathologie
During the last 30 years many advances have been made in kidney tumor pathology. In 1981, 9 entities were recognized in the WHO Classification. In the latest classification of 2004, 50 different types have been recognized. Additional tumor entities have been described since and a wide variety of prognostic parameters have been investigated with var...