EGFR is involved in control of gastric cell proliferation through activation of MAPK and Src signalling pathways in earl...
FAPESP[03/12941-2]
EGFR is involved in control of gastric cell proliferation through activation of MAPK and Src signalling pathways in earl...
FAPESP[03/12941-2]
EGFR is involved in control of gastric cell proliferation through activation of MAPK and Src signalling pathways in earl...
FAPESP[03/12941-2]
Small Intestinal Na+,K+-Adenosine Triphosphatase Activity and Gene Expression in Experimental Diabetes Mellitus
Published in Digestive Diseases and Sciences
The Na+,K+-ATPase plays akey role in the absorption of electrolytes, water, andnutrients from the small intestine. The effect ofstreptozotocin-induced diabetes mellitus (STZ-DM) on theactivity and expression of Na+,K+-ATPase in therat small intestine was examined in the present study.Diabetes mellitus was induced by a singleintraperitoneal injectio...
Identification and Characterization of a Novel Rat Triosephosphate Isomerase Gene in Remnant Ileum After Massive Small B...
Published in Digestive Diseases and Sciences
This paper describes the identification andcharacterization of a novel cDNA encoding a putativeprotein of 254 amino acids that is highly homologous totriosephosphate isomerase. The cDNA was isolated by subtractive hybridization and wasdifferentially expressed in the remnant rat ileum aftermassive small bowel resection. The novel triosephosphateisom...
Factors Affecting Outcome Following Proximal and Distal Intestinal Resection in the Dog (An Examination of the Relative ...
Published in Digestive Diseases and Sciences
In the clinical setting, resection of the ileumresults in an inferior functional outcome compared tojejunal resection. This may be related to a greateradaptive capacity of the ileum, intrinsic structural and functional differences, or regionaldifferences in motor and hormonal function. Our aim wasto evaluate the relative contributions of these fact...
Systemic Short-Chain Fatty Acids Rapidly Alter Gastrointestinal Structure, Function, and Expression of Early Response Ge...
Published in Digestive Diseases and Sciences
Luminal and systemic short chain fatty acids (SCFA) stimulate mucosal proliferation but the mechanism(s) is unclear. This study examined acute effects of systemic SCFAs on gastrointestinal structure and function and signals potentially mediating SCFA-induced mucosal proliferation. Male Sprague-Dawley rats (246 ± 2 g) received nutrients as either st...
Nerve Terminals Containing Neuropeptides Decrease in Number After Massive Proximal Small Bowel Resection in the Piglet
Published in Digestive Diseases and Sciences
The aim of this study was to evaluate possiblechanges in the neuropeptide innervation pattern of theremaining porcine ileum following 75% proximal resectionof the small intestine. Three-month-old piglets were operated on and two months postoperativelyfullthickness specimens of the proximal part of thedistal ileum wall were taken. Age-matched 3- and...
