Engelen, F Thiry, D Devleesschauwer, B Heyndrickx, M Mainil, J De Zutter, L Cox, E
Published in
Journal of applied microbiology
The purpose of this study was to investigate the occurrence of Escherichia coli O157 and O26 on Belgian dairy cattle farms, the presence of virulence genes in the confirmed isolates and the association of E. coli O26 presence with calf diarrhoea. In total, 233 recto-anal mucosal swabs (RAMS) were obtained from healthy and diarrheic dairy calves on ...
Plessers, Sander; 125352; Van Deuren, Vincent; 111168; Lavigne, Rob; Robben, Johan; 5880;
The combination of phage display technology with high-throughput sequencing enables in-depth analysis of library diversity and selection-driven dynamics. We applied short-read sequencing of the mutagenized region on focused display libraries of two homologous nucleic acid modification eraser proteins-AlkB and FTO-biopanned against methylated DNA. T...
Becce, M Kloeckner, A Higgins, S Penders, J Hachim Diaz, DJ Bashor, CJ Edwards, A Stevens, M
We investigated the biomaterial interface between the bacteria Escherichia coli DH5α and silicon nanowire patterned surfaces. We optimised the engineering of silicon nanowire coated surfaces using metal-assisted chemical etching. Using a combination of focussed ion beam scanning electron microscopy, and cell viability and transformation assays, we ...
Huijghebaert, Suzy; Vanham, Guido; Van Winckel, Myriam; Allegaert, Karel; 46648;
BACKGROUND: nasal or oral sprays are often marketed as medical devices (MDs) in the European Union to prevent common cold (CC), with ColdZyme®/Viruprotect® (trypsin/glycerol) mouth spray claiming to prevent colds and the COVID-19 virus from infecting host cells and to shorten/reduce CC symptoms as an example. We analyzed the published (pre)-clinica...
Tabasi, Maryam; Nombela, Ivan; 134924; Janssens, Julie; 117020; Lahousse, Adrien P; Christ, Frauke; 45105; Debyser, Zeger; 3374;
The HIV replication cycle depends on the interaction of viral proteins with proteins of the host. Unraveling host-pathogen interactions during the infection is of great importance for understanding the pathogenesis and the development of antiviral therapies. To date HIV uncoating and nuclear import are the most debated steps of the HIV-1 replicatio...
Zheng, Yue; Yang, Xian-Wen; Schols, Dominique; 9441; Mori, Mattia; Botta, Bruno; Chevigne, Andy; Mulinge, Martin; Steinmetz, Andre; Schmit, Jean-Claude; Seguin-Devaux, Carole;
...
Cassia abbreviata is widely used in Sub-Saharan Africa for treating many diseases, including HIV-1 infection. We have recently described the chemical structures of 28 compounds isolated from an alcoholic crude extract of barks and roots of C. abbreviata, and showed that six bioactive compounds inhibit HIV-1 infection. In the present study, we demon...
Toledo-Silva, Bruno de Souza, Fernando Nogueira Piepers, Sofie Mertens, Kristien Haesebrouck, Freddy De Vliegher, Sarne
Published in
Veterinary Research
Communications via quorum sensing (QS) between non-aureus staphylococci (NAS) and Staphylococcus (S.) aureus in the bovine mammary gland remains largely unexplored. We determined whether 34 S. chromogenes, 11 S. epidermidis, and 14 S. simulans isolates originating from bovine milk samples and teat apices were able to regulate the QS of S. aureus, a...
Schlapbach, LJ Andre, MC Grazioli, S Schobi, N Ritz, N Aebi, C Agyeman, P Albisetti, M Bailey, DGN Berger, C
...
Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndrome in Children (MIS-C). In the absence of trials, evidence for treatment remains scarce. Purpose: T...
Simoens, Steven; 43289; Bento-Abreu, Andre; Merckx, Barbara; Joubert, Sophie; Vermeersch, Steve; Pavelyev, Andrew; Varga, Stefan; Morais, Edith;
Background: Routine human papillomavirus (HPV) immunization in Belgium is currently regionally managed, with school-aged girls receiving the 9-valent HPV (9vHPV) vaccine in Flanders and Wallonia-Brussels with a national catch-up program for females only. This study will assess whether expanding these programs to gender-neutral vaccination (GNV) wit...
Meerstein-Kessel, Lisette; Venhuizen, Jeron; Garza, Daniel; 139894; Proellochs, Nicholas I; Vos, Emma J; Obiero, Joshua M; Felgner, Philip L; Sauerwein, Robert W; Peters, Marynthe; Yang, Annie SP;
...
Plasmodium species, the causative agent of malaria, have a complex life cycle involving two hosts. The sporozoite life stage is characterized by an extended phase in the mosquito salivary glands followed by free movement and rapid invasion of hepatocytes in the human host. This transmission stage has been the subject of many transcriptomics and pro...
