Farhat, Sarah Le, Phuong Kayal, Ehsan Noel, Benjamin Bigeard, Estelle Corre, Erwan Maumus, Florian Florent, Isabelle Alberti, Adriana Aury, Jean-Marc
...
Published in
BMC Biology
BackgroundDinoflagellates are aquatic protists particularly widespread in the oceans worldwide. Some are responsible for toxic blooms while others live in symbiotic relationships, either as mutualistic symbionts in corals or as parasites infecting other protists and animals. Dinoflagellates harbor atypically large genomes (~ 3 to 250 Gb), with gene...
Ross, Alastair Brunius, Carl Chevallier, Olivier Dervilly, Gaud Elliott, Chris Guitton, Yann Prenni, Jessica E Savolainen, Otto Hemeryck, Lieselot Vidkjær, Nanna Hjort
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Published in
Meat science
Increasing demands are being placed on meat producers to verify more about their product with regards to safety, quality and authenticity. There are many methods that can detect aspects of these parameters in meat, yet most are too slow to keep up with the demands of modern meat processing plants and supply chains. A new technology, Rapid Evaporati...
Ma, Xin; Xie, Mei; Suykens, Johan AK; 15385;
status: published
Smith, Benjamin A. Gelles, Jeff Goode, Bruce L.
Published in
Methods in Enzymology
The actin cytoskeleton is very dynamic and highly regulated by multiple associated proteins in vivo. Understanding how this system of proteins functions in the processes of actin network assembly and disassembly requires methods to dissect the mechanisms of activity of individual factors and of multiple factors acting in concert. The advent of sing...
De Meyer, Margaux Fijalkowski, Igor Jonckheere, Veronique De Sutter, Delphine Eyckerman, Sven Van Damme, Petra
In the context of host-pathogen interactions, gram-negative bacterial virulence factors, such as effectors, may be transferred from bacterial to eukaryotic host cytoplasm by multicomponent Type III protein secretion systems (T3SSs). Central to Salmonella enterica serovar Typhimurium (S. Typhimurium) pathogenesis is the secretion of over 40 effector...
Trillet, Kilian; Jacobs, Kathryn A; 138395; Andre-Gregoire, Gwennan; Thys, An; Maghe, Clement; Cruard, Jonathan; Minvielle, Stephane; Diest, Sara Gonzalez; Montagnac, Guillaume; Bidere, Nicolas;
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Glioblastoma is one of the most lethal forms of adult cancer, with a median survival of ∼15 mo. Targeting glioblastoma stem-like cells (GSCs) at the origin of tumor formation and relapse may prove beneficial. In situ, GSCs are nested within the vascular bed in tight interaction with brain endothelial cells, which positively control their expansion....
Roussel, Charlène De Paepe, Kim Galia, Wessam De Bodt, Jana Chalancon, Sandrine Denis, Sylvain Leriche, Francoise Vandekerkove, Pascal Ballet, Nathalie Blanquet-Diot, Stephanie
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Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of acute traveler's diarrhea. Adhesins and enterotoxins constitute the major ETEC virulence traits. With the dramatic increase in antibiotic resistance, probiotics are considered a wholesome alternative to prevent or treat ETEC infections. Here, we examined the antimicrobial p...
Politi, Emanuele; 133319; Bennour, Salomon; Lueders, Adrian; Manatschal, Anita; Green, Eva GT;
status: published
Thery, Fabien Eggermont, Denzel Impens, Francis
During infection, pathogen sensing and cytokine signaling by the host induce expression of antimicrobial proteins and specialized post-translational modifications. One such protein is ISG15, a ubiquitin-like protein (UBL) conserved among vertebrates. Similar to ubiquitin, ISG15 covalently conjugates to lysine residues in substrate proteins in a pro...
Sostaric, Nikolina; Arslan, Ahmed; Carvalho, Bernardo; Plech, Marcin; Voordeckers, Karin; Verstrepen, Kevin J; 31931; van Noort, Vera; 89822;
For yeast cells, tolerance to high levels of ethanol is vital both in their natural environment and in industrially relevant conditions. We recently genotyped experimentally evolved yeast strains adapted to high levels of ethanol and identified mutations linked to ethanol tolerance. In this study, by integrating genomic sequencing data with quantit...
