Citerio, Giuseppe Robba, Chiara Rebora, Paola Petrosino, Matteo Rossi, Eleonora Malgeri, Letterio Stocchetti, Nino Galimberti, Stefania Menon, David K. Åkerlund, Cecilia
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Published in
Intensive Care Medicine
Purpose To describe the management of arterial partial pressure of carbon dioxide (PaCO2) in severe traumatic brain-injured (TBI) patients, and the optimal target of PaCO2 in patients with high intracranial pressure (ICP). Methods Secondary analysis of CENTER-TBI, a multicentre, prospective, observational, cohort study. The primary aim was to descr...
Mattozzi, Simone Cerminara, Caterina Sotgiu, Maria A. Carta, Alessandra Coniglio, Antonella Roberto, Denis Simula, Delia M. Luca Pruneddu, Gian Dell'Avvento, Silvia Muzzu, S. Sonia
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Published in
Clinical Neurophysiology Practice
Background Typical absence seizures (AS) are epileptic phenomena typically appearing in children 4–15 years of age and can be elicited by hyperventilation (HV). Hyperventilation-induced high-amplitude rhythmic slowing (HIHARS) represents a paraphysiological response during HV and may manifest with alteration of awareness (HIHARSAA). To date, HIHARS...
Vakaet, Vincent Van Hulle, Hans Schoepen, Max Van Caelenberg, Els Van Greveling, Annick Holvoet, Jeroen Monten, Christel De Baerdemaeker, Luc De Neve, Wilfried Coppens, Marc
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Background and purpose: Deep inspiration breath-hold is an established technique to reduce heart dose during breast cancer radiotherapy. However, modern breast cancer radiotherapy techniques with lymph node irradiation often require long beam-on times of up to 5 min. Therefore, the combination with deep inspiration breath-hold (DIBH) becomes challe...
Huijben, Jilske A. Dixit, Abhishek Stocchetti, Nino Maas, Andrew I. R. Lingsma, Hester F. van der Jagt, Mathieu Nelson, David Citerio, Giuseppe Wilson, Lindsay Menon, David K.
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Published in
Critical Care
PurposeTo study variation in, and clinical impact of high Therapy Intensity Level (TIL) treatments for elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI) across European Intensive Care Units (ICUs).MethodsWe studied high TIL treatments (metabolic suppression, hypothermia (
Shastri, Lisha Kjærgaard, Søren Thyrrestrup, Peter S. Rees, Stephen E. Thomsen, Lars P.
Published in
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background ABGs are performed in acute conditions as the reference method for assessing the acid-base status of blood. Hyperventilation and breath-holding are common ventilatory changes that occur around the time of sampling, rapidly altering the ‘true’ status of the blood. This is particularly relevant in emergency medicine patients without perman...
Hurvitz, Manju Weinberger, Miles
Published in
Pediatric clinics of North America
Functional respiratory disorders (FRDs) are those characterized by respiratory symptoms without anatomic or organic etiology. Clinicians caring for children encounter these disorders and should be familiar with diagnosis and treatment. FRDs encompass the habit cough syndrome and its variants, vocal cord dysfunction, hyperventilation disorders, func...
Spagnoli, Carlotta Rizzi, Susanna Salerno, Grazia Gabriella Frattini, Daniele Koskenvuo, Juha Fusco, Carlo
Published in
Molecular Syndromology
Abnormal breathing patterns are a typical feature of Rett and Pitt-Hopkins syndrome and their variants. Their treatment can be challenging, with a risk of long-term detrimental consequences. Early infantile epileptic encephalopathy (EIEE) type 54 is a rare epileptic encephalopathy caused by pathogenic variants in the heterogeneous nuclear ribonucle...
Sadler, Charlotte Brett, Kaighley Heerboth, Aaron Swisher, Austin R Mehregani, Nader Touriel, Ross Cannon, Daniel T
Published in
Diving and hyperbaric medicine
There is no required training for breath-hold diving, making dissemination of safety protocols difficult. A recommended breath-hold dive time limit of 60 s was proposed for amateur divers. However, this does not consider the metabolic-rate dependence of oxygen stores depletion. We aimed to measure the effect of apnoea time and metabolic rate on art...
Huijben, Jilske A. Dixit, Abhishek Stocchetti, Nino Maas, Andrew I. R. Lingsma, Hester F. van der Jagt, Mathieu Nelson, David Citerio, Giuseppe Wilson, Lindsay Menon, David K.
...
Abstract: Purpose: To study variation in, and clinical impact of high Therapy Intensity Level (TIL) treatments for elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI) across European Intensive Care Units (ICUs). Methods: We studied high TIL treatments (metabolic suppression, hypothermia (
Kaplan, Alicia Mannarino, Anthony P Nickell, P V
Published in
Applied psychophysiology and biofeedback
Panic disorder (PD) is a debilitating condition that drives medical spending at least twice as high as medically matched controls. Excessive utilization of healthcare resources comes from emergency department (ED), medications, diagnostic testing, and physician visits. Freespira is an FDA-cleared digital therapeutic that treats PD and panic attacks...
