Liu, Jing Li, Jing Xia, Chunchao He, Wenzhang Li, Xue Shen, Sumin Zhou, Xiaoyue Tong, Nanwei Peng, Liqing
Published in
Cardiovascular diabetology
Obesity is often associated with multiple comorbidities. However, whether obese subjects with hyperlipidemia in the absence of other complications have worse cardiac indices than metabolically healthy obese subjects is unclear. Therefore, we aimed to determine the effect of hyperlipidemia on subclinical left ventricular (LV) function in obesity and...
Laffin, Luke J Nissen, Steven E
Published in
Trends in cardiovascular medicine
Lipoprotein(a) (Lp(a)) is an increasingly discussed and studied risk factor for atherosclerotic cardiovascular disease and aortic valve stenosis. Many genetic and epidemiological studies support the important causal role that Lp(a) plays in the incidence of cardiovascular disease. Although dependent upon the threshold and unit of measurement of Lp(...
Hu, Yingying Xu, Run Feng, Jing Zhang, Qingwei Zhang, Lifu Li, Yiyang Sun, Xiuxiu Gao, Jin Chen, Ximing Du, Menghan
...
Published in
The Journal of nutritional biochemistry
Hyperlipidemia (HLP) is a prevalent metabolic disorder and a significant risk factor for cardiovascular disease. According to recent discoveries, super-enhancers (SEs) play a role in the increased expression of genes that encode important regulators of both cellular identity and the progression of diseases. However, the underlying function of SEs i...
Lu, Xiao-Rong Tao, Qi Qin, Zhe Liu, Xi-Wang Li, Shi-Hong Bai, Li-Xia Ge, Wen-Bo Liu, Ya-Xian Li, Jian-Yong Yang, Ya-Jun
...
Published in
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hyperlipidemia caused by abnormal lipid metabolism has reached epidemic proportions. This phenomenon is also common in companion animals. Previous studies showed that AEE significantly improves abnormal blood lipids in hyperlipidemia rats and mice, but its mechanism is still not clear enough. In this study, the mechanism and potential key pathways ...
Yin, Na Wu, Xiaoping Ren, Rongrong Luo, Jing
Published in
Biotechnology & genetic engineering reviews
There is no consensus on whether acupoint catgut embedding should be widely used as a treatment for hyperlipidemia. Acupoint catgut embedding is also not included in the guidelines for the treatment of hyperlipidemia. The purpose of this study was of two aspects: 1) to review recent research advances in the relationship between acupoint catgut embe...
Ros Thorisdottir, Yrsa
Hematology analyzers can be used for screening patients for blood abnor-malities. The techniques used in a hematology analyzer include impedanceanalysis, flow cytometry and spectroscopy, which allow for measuring of forexample absolute count, sizes and concentration of different cells in a patient’sblood sample. Hyperlipidemia, which refers to elev...
Yang, Zhenyu Li, Jixin Zhou, Bogeng Ji, Xuan Yuan, Jianying Yan, Junchen Nan, Xilei Guo, Dandan
Published in
Chinese medicine
To evaluate the clinical efficacy and safety of commonly used oral Chinese patent medicines for the treatment of coronary heart disease combined with hyperlipidemia in clinical practice through a network meta-analysis. PubMed, Embase, Cochrane Library, Web of Science, Wanfang, VIP, SinoMed, and CNKI databases were searched for all published randomi...
Han, Wenrun Zhang, Dandan Zhang, Peng Tao, Qianqian Du, Xiaoli Yu, Chunquan Dong, Pengzhi Zhu, Yan
Published in
BMC complementary medicine and therapies
Liver X Receptor (LXR) agonists could attenuate the development of atherosclerosis but bring excess lipid accumulation in the liver. Danlou Recipe was believed to be a benefit for improving the lipid profile. Thus, it is unclear whether Danlou Recipe could attenuate hyperlipidemia without excess lipid accumulated in the liver of mice. This study ai...
Meng, Meng Wang, Jiaying Wang, Changyuan Zhao, Jianyu Wang, Huihan Zhang, Yukun Sun, Huijun Liu, Mozhen
Published in
Calcified tissue international
In hyperlipidemia-induced osteoporosis, bone marrow mesenchymal stem cells (BMSCs) differentiate into more adipocytes than osteoblasts, leading to decreased bone formation. It is vital to elucidate the effects of hyperlipidemia on bone metabolism and seek new agents that regulate adipocyte-osteoblast lineage allocation. CoQ10, a rate-limiting coenz...
Li, Yumiao Zhang, Yan Zhang, Yu Lin, Tianfeng Gao, Yanyan Cai, Yuan Zhou, Chang Yang, Leyi Liu, Bin Dong, Shifen
...
Published in
Pharmaceutical biology
Jiang-Zhi-Ning (JZN), a traditional Chinese medicinal formula, is used to treat hyperlipidemia in clinics. To screen the hypolipidemic "bioequivalent substance system (BSS)" of JZN and elucidate the potential hypolipidemic mechanism. In vitro, the TG content in HepG2 cells was determined after the intervention of the combination of advantageous com...
