Gagala, Jacek
Published in
BMC Musculoskeletal Disorders
Background Aseptic loosening is the most frequent indication for revision of total hip arthroplasty. Revision arthroplasty of acetabular component is a challenge for every surgeon because they have to simultaneously deal with the reconstruction of bone defects, adequate implant geometry and stable fixation. Allografts are the most frequently used m...
Liu, Fan Kang, Honglei Liu, Zhiwei Jin, Siyang Yan, Guoping Sun, Yunlong Li, Feng Zhan, Haifei Gu, Yuantong
3D Printed biodegradable polymeric scaffolds are critical to repair a bone defect, which can provide the individual porous and network microenvironments for cell attachment and bone tissue regeneration. Biodegradable PCL/HA composites were prepared with the blending of poly(ε-caprolactone) (PCL) and hydroxyapatite nanoparticles (HA). Subsequently, ...
Singh, Angaraj Dubey, Ashutosh Kumar
Published in
Journal of biomaterials applications
The bacterial contamination in implants has been recognized as one of the key issues in orthopedics. In this article, a new technique of electrical polarization of various non-piezoelectric and piezoelectric biocompatible ceramics has been explored to develop antibacterial implants. Optimally processed hydroxyapatite (HA), BaTiO3 (BT), CaTiO3 (CT),...
Jokisaari, Jacob Hu, Xuan Mukherjee, Arijita Uskokovic, Vuk Klie, Robert F
Published in
Nanotechnology
Liquid cell electron microscopy is an imaging technique allowing for the investigation of the interaction of liquids and solids at nanoscopic length scales. Such in situ observations are increasingly in-demand in an array of fields, from biological sciences to medicine to batteries. Graphene liquid cells (GLCs), in particular, have generated a grea...
Zhongxing, Liu Shaohong, Wu Jinlong, Li Limin, Zhang Yuanzheng, Wang Haipeng, Gao Jian, Cao
Published in
Journal of Biological Engineering
The development of an effective scaffold for bone defect repair is an urgent clinical need. However, it is challenging to design a scaffold with efficient osteoinduction and antimicrobial activity for regeneration of bone defect. In this study, we successfully prepared a hydroxyapatite (HA) porous scaffold with a surface-specific binding of peptide...
Scocozza, Franca Sakaj, Mirena Auricchio, Ferdinando Marconi, Stefania Riello, Pietro Ferrari, Cinzia Cansolino, Laura Catenacci, Laura Sorrenti, Milena Scatto, Marco
...
Published in
Journal of Polymer Research
Polycaprolactone (PCL) and hydroxyapatite (HA) composite are widely used in tissue engineering (TE). They are fit to being processed with three-dimensional (3D) printing technique to create scaffolds with verifiable porosity. The current challenge is to guarantee the reliability and reproducibility of 3D printed scaffolds and to create sterile scaf...
Rahmani-Moghadam, Ebrahim Talaei-Khozani, Tahereh Zarrin, Vahideh Vojdani, Zahra
Published in
BioMedical Engineering OnLine
BackgroundPhytochemical agents such as thymoquinone (TQ) have osteogenic property. This study aimed to investigate the synergic impact of TQ and hydroxyapatite on mesenchymal stem cell differentiation. Alginate was also used as drug vehicle.MethodsHA scaffolds were fabricated by casting into polyurethane foam and sintering at 800 °C, and then, 1250...
Jin, Yuan-Zhe Zheng, Guang-Bin Lee, Jae Hyup Han, Shi-Huan
Published in
Biomaterials Research
BackgroundAutograft has been widely used in various orthopedic and dental surgery for its superior osteogenicity, osteoinductivity and osteoconductivity. But the available volume of the autograft is limited and the efficacy of it is highly affected by the condition of the patients. Therefore, growth factors such as Escherichia coli bone morphogenet...
Agalya, P. Suresh Kumar, G. Srinivasan, Ramalingam Prabu, K. M. Karunakaran, Gopalu Cholan, S. Kolesnikov, Evgeny Kim, Myunghee
Published in
Applied Physics A
We report the synthesis of hydroxyapatite (HAp)-based antibacterial biomaterials using a mussel shell as a calcium source and by the integration of silver ions via a wet precipitation method. The silver doping at 2 mol% can provide silver-doped carbonated HAp while at 10 mol% can offer silver-doped carbonated HAp/silver oxide nanocomposite. The syn...
Akbari-Aghdam, Hossein Bagherifard, Abolfazl Motififard, Mehdi Parvizi, Javad Sheikhbahaei, Erfan Esmaeili, Saeid Saber-Samandari, Saeed Khandan, Amirsalar
Published in
Archives of Bone and Joint Surgery
Background: Although bone tissue has the unique characteristic of self-repair in fractures, bone grafting is needed in some situations. The synthetic substances that are used in such situations should bond to the porous bones, be biocompatible and biodegradable, and do not stimulate the immune responses. Biomaterial engineering is the science of fi...
