Chato-Astrain, Jesús Chato-Astrain, Isabel Sánchez-Porras, David García-García, Óscar-Darío Bermejo-Casares, Fabiola Vairo, Claudia Villar-Vidal, María Gainza, Garazi Villullas, Silvia Oruezabal, Roke-Iñaki
...
Published in
Journal of Nanobiotechnology
BackgroundTreatment of patients affected by severe burns is challenging, especially due to the high risk of Pseudomonas infection. In the present work, we have generated a novel model of bioartificial human dermis substitute by tissue engineering to treat infected wounds using fibrin-agarose biomaterials functionalized with nanostructured lipid car...
Vijayan, Suvarna Mini Göen, Thomas Dennerlein, Kathrin Horch, R E Ludolph, I Drexler, Hans Kilo, Sonja
Published in
Toxicology in vitro : an international journal published in association with BIBRA
The fluoride ions of the industrially largely irreplaceable, locally corrosive hydrofluoric acid (HF) can scavenge cations in biological tissues, which explains their high toxic potential, and also leads to local acidification through proton release. The influence of three complexing agents, calcium (Ca2+) gluconate (as 2.5% Ca2+gel and individuall...
Hama, Tetsuya Kouchi, Akira Watanabe, Naoki Shioya, Nobutaka Shimoaka, Takafumi Hasegawa, Takeshi
Published in
Biophysical chemistry
An in vivo analysis of stearyl alcohol and stearic acid films on the skin surface using polarized infrared-external reflection spectroscopy revealed that whether the sample molecules adopt an energetically stable conformation and orientation strongly depends on the molecular functionalities and sample preparation conditions. For stearic acid, even ...
Chen, Bin Genovese, Katia Pan, Bing
Published in
Journal of the mechanical behavior of biomedical materials
Panoramic shape and deformation measurements of human skin in vivo may provide important information for biomechanical analysis, exercise guidance and medical diagnosis. This work proposes the application of an advanced mirror-assisted multi-view digital image correlation (DIC) method for dynamic measurements of 360-deg shape and deformation of hum...
Hunt, Chris O Morawska, Zuzanna
Published in
Review of palaeobotany and palynology
Pollen retention on clothes, footwear, hair and body has been used to link people to localities with distinctive vegetation, or soils containing distinctive palynomorphs. Little attention has been given to human skin as a possible medium for carrying a forensically important pollen load and whether this might survive attempts to remove it. We repor...
Moon, Hye-Rim Jung, Joon Min Kim, Su Yeon Song, Youngsup Chang, Sung Eun
Published in
Journal of dermatological science
Ultraviolet radiation (UVR) is the most well-known cause of skin pigmentation accompanied with photoaging. Transforming growth factor (TGF)-β1 was previously shown to have anti-melanogenic property; however, it can induce scarring in skin. We investigated the effect of TGF-β3 on melanogenesis in human melanocytes cocultured with UV-irradiated skin ...
Pelegrino, Milena T Paganotti, André Seabra, Amedea B Weller, Richard B
Published in
Histochemistry and cell biology
Nitric oxide (NO) is related to a wide range of physiological processes such as vasodilation, macrophages cytotoxicity and wound healing. The human skin contains NO precursors (NOx). Those are mainly composed of nitrite (NO2-), nitrate (NO3-), and S-nitrosothiols (RSNOs) which forms a large NO store. These NOx stores in human skin can mobilize NO t...
Silva, Mariana Freitas, Bruno Andrade, Renato Espregueira-Mendes, João Silva, Filipe Carvalho, Óscar Flores, Paulo
Published in
Annals of biomedical engineering
The purpose of this systematic review is to analyze characteristics and methodologies utilized in bioheat transfer models of human skin to provide state-of-the-art knowledge on the topic. This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. PubMed, EMBASE and Web of Science databa...
Badihi, Amit Frušić-Zlotkin, Marina Soroka, Yoram Benhamron, Sandrine Tzur, Tomer Nassar, Taher Benita, Simon
Published in
Nanomedicine : nanotechnology, biology, and medicine
Systemic cyclosporine A (CsA) therapy shows efficacy in the treatment of recalcitrant severe atopic dermatitis (AD) but elicits severe side-effects. Thus, a topical formulation of CsA nanocapsules (NCs), able to potentially bypass these drawbacks, was developed. CsA-NCs were shown to enhance drug penetration into the various layers of porcine ear s...
Siiskonen, Hanna Scheffel, Jörg
Published in
Methods in molecular biology (Clifton, N.J.)
Mast cells are intriguing immune cells monitoring the interfaces of our body with the environment. Long-term cultures of mast cells originating from hematological malignant cells have been traditionally used to investigate mast cell biology, but these cells are not optimal to study the characteristics of human skin mast cells because of their origi...
