Ma, Si-Yuan Zhao, Ning Cui, Lele Li, Ying Zhang, Hang Wang, Jing Pang, Jie Wang, Ming Wang, Chengshuo Ying, Sun
...
Published in
Stem cell reviews and reports
Allergic rhinitis and allergic asthma are the most common type-2 inflammatory diseases, which are hardly curable and cause heavy burden to general well-being. Mesenchymal stem cells (MSCs) are multipotent nonhematopoietic cells with potential immunomodulatory effects that have been showning to have a therapeutic effect on allergic diseases. Here, w...
de Loor, Henriette; 42293; Smout, Dieter; 149739; Jorgensen, Hanne; Meng, Catarina; Van Craenenbroeck, Amaryllis H; 128244; Evenepoel, Pieter; 34199;
The molecular mechanisms underlying metabolic bone diseases, including renal osteodystrophy, are poorly understood. Transcriptomics are increasingly used to characterize biological molecular networks and prove promising in identifying therapeutic targets and biomarkers. A reliable method for obtaining sufficient amounts of high quality RNA from hum...
Segura, Elodie
Published in
European journal of immunology
Human DCs have been divided into several subsets based on their phenotype and ontogeny. Recent high throughput single-cell methods have revealed additional heterogeneity within human DC subsets, and new subpopulations have been proposed. In this review, we provide an updated view of the human DC subsets and of their ontogeny supported by recent cli...
Vogelsang, Eric M Polonijo, Andrea N
BackgroundAlthough more than half of older adults receive the annual influenza vaccine (flu shot), only about one-third have ever been vaccinated for shingles. With this in mind, our study examines how the associations between sociodemographic characteristics, health behaviors, and vaccine uptake differ between these two viruses. In doing so, it al...
Kir, M C Onal, M O Uluer, E T Ulman, C Inan, S
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Bone healing deficiencies are challenging for orthopedic practice. The use of stem cells with scaffolds to treat bone tissue losses currently is popular for promoting regeneration of tissue. Programmable cells of monocytic origin (PCMO) may differentiate into three germ layers and may be a promising alternative treatment due to their stem cell-like...
Dawood, Yousif; Buijtendijk, Marieke FJ; Shah, Harsha; Smit, Johannes A; Jacobs, Karl; Hagoort, Jaco; Oostra, Roelof-Jan; Bourne, Tom; 56124; van den Hoff, Maurice JB; de Bakker, Bernadette S;
...
Due to advancements in ultrasound techniques, the focus of antenatal ultrasound screening is moving towards the first trimester of pregnancy. The early first trimester however remains in part, a 'black box', due to the size of the developing embryo and the limitations of contemporary scanning techniques. Therefore there is a need for images of earl...
Dawood, Yousif Buijtendijk, Marieke F J Shah, Harsha Smit, Johannes A Jacobs, Karl Hagoort, Jaco Oostra, Roelof-Jan Bourne, Tom van den Hoff, Maurice J B de Bakker, Bernadette S
...
Published in
Seminars in cell & developmental biology
Due to advancements in ultrasound techniques, the focus of antenatal ultrasound screening is moving towards the first trimester of pregnancy. The early first trimester however remains in part, a 'black box', due to the size of the developing embryo and the limitations of contemporary scanning techniques. Therefore there is a need for images of earl...
Czukiewska, Sylwia M Chuva de Sousa Lopes, Susana M
Published in
Seminars in cell & developmental biology
Gametes are cells that have the unique ability to give rise to new individuals as well as transmit (epi)genetic information across generations. Generation of functionally competent gametes, oocytes and sperm cells, depends to some extent on several fundamental processes that occur during fetal development. Direct studies on human fetal germ cells r...
Lim, Y Z Wang, Y Estee, M Abidi, J Udaya Kumar, M Hussain, S M Wluka, A E Little, C B Cicuttini, F M
Published in
Osteoarthritis and cartilage
Osteoarthritis causes significant pain and disability with no approved disease-modifying drugs. We systematically reviewed the evidence from both pre-clinical and human studies for the potential disease-modifying effect of metformin in osteoarthritis. Ovid Medline, Embase and CINAHL were searched between inception and June 2021 using MeSH terms and...
Nakashima, Yoshiki Miyagi-Shiohira, Chika Saitoh, Issei Watanabe, Masami Matsushita, Masayuki Tsukahara, Masayoshi Noguchi, Hirofumi
Published in
iScience
Human hepatocytes were transfected with Sendai virus vectors (SeV) expressing OCT3/4, SOX2, KLF4, and C-MYC to produce hepatocyte-derived induced pluripotent stem cells (iPSCs). The messenger RNA (mRNA) expression of undifferentiated markers (passage 19-21) and hepatocyte-specific markers (HSMs) (passage 0-20) in 48 established hepatocyte-derived i...
