Morales Fénero, Camila Sacksteder, Raina Diamos, Andrew Kimmey, Jacqueline
The circadian clock is a cell-autonomous process that regulates daily internal rhythms by interacting with environmental signals. Reports across species show that infection can alter the expression of circadian genes; however, in teleosts, these effects are influenced by light exposure. Currently, no reports analyze the direct effects of bacterial ...
Posch, Bradley Bush, Susan Koepke, Dan Schuessler, Alexandra Anderegg, Leander Aparecido, Luiza Blonder, Benjamin Guo, Jessica Kerr, Kelly Moran, Madeline
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Increasing heatwaves are threatening forest ecosystems globally. Leaf thermal regulation and tolerance are important for plant survival during heatwaves, though the interaction between these processes and water availability is unclear. Genotypes of the widely distributed foundation tree species Populus fremontii were studied in a controlled common ...
González-González, Andrea Batarseh, Tiffany N Rodríguez-Verdugo, Alejandra Gaut, Brandon S
Epistasis is caused by genetic interactions among mutations that affect fitness. To characterize properties and potential mechanisms of epistasis, we engineered eight double mutants that combined mutations from the rho and rpoB genes of Escherichia coli. The two genes encode essential functions for transcription, and the mutations in each gene were...
Chandel, Avinash DeBeaubien, Nicolas A Ganguly, Anindya Meyerhof, Geoff T Krumholz, Andreas A Liu, Jiangqu Salgado, Vincent L Montell, Craig
Mosquito-borne diseases affect hundreds of millions of people annually and disproportionately impact the developing world1,2. One mosquito species, Aedes aegypti, is a primary vector of viruses that cause dengue, yellow fever and Zika. The attraction of Ae. aegypti female mosquitos to humans requires integrating multiple cues, including CO2 from br...
Cheon, Hyejeong Lee Kizilova, Nataliya Flekkøy, Eirik G Mason, Matthew J Folkow, Lars P Kjelstrup, Signe
We report the effects of varying physiological and other properties on the heat and water exchange in the maxilloturbinate structure (MT) of the bearded seal (Erignathus barbatus or Eb) in realistic environments, using a computational fluid dynamics (CFD) model. We find that the water retention in percent is very high (about 90 %) and relatively un...
Liang, Jiexin Batali, Mackenzie Routt, Catherine Ristenpart, William Guinard, Jean-Xavier
With the growing popularity of cold brewed coffee comes a need for brewing efficiency while preserving the desirable flavor profile. Despite the wide use of full immersion brewing techniques, the effect of brew time on the dynamic sensory profiles of full immersion brewed coffee remains underexplored. Here, we investigated the relationship between ...
Sheridan, Scott De Guzman, Edith Eisenman, David Sailor, David Parfrey, Jonathan Kalkstein, Laurence
There is an urgent need for strategies to reduce the negative impacts of a warming climate on human health. Cooling urban neighborhoods by planting trees and vegetation and increasing albedo of roofs, pavements, and walls can mitigate urban heat. We used synoptic climatology to examine how different tree cover and albedo scenarios would affect heat...
Sinclair, Gabriela Galarneau, Erin R Hnizdor, Josh F McElrone, Andrew J Walker, Michael Andrew Bartlett, Megan K
Background and aimsMany agricultural areas are expected to face hotter, drier conditions from climate change. Understanding the mechanisms that crops use to mitigate these stresses can guide breeding for more tolerant plant material. We tested relationships between traits, physiological function in hot conditions and historical climate associations...
Rogne, Tormod Wang, Rong Wang, Pin Deziel, Nicole Metayer, Catherine Wiemels, Joseph Chen, Kai Warren, Joshua Ma, Xiaomei
BACKGROUND: High ambient temperature is increasingly common due to climate change and is associated with risk of adverse pregnancy outcomes. Acute lymphoblastic leukaemia is the most common malignancy in children, the incidence is increasing, and in the USA disproportionately affects Latino children. We aimed to investigate the potential associatio...
Dimitrova, Asya Dimitrova, Anna Mengel, Matthias Gasparrini, Antonio Lotze-Campen, Hermann Gabrysch, Sabine
Exposure to high and low ambient temperatures increases the risk of neonatal mortality, but the contribution of climate change to temperature-related neonatal deaths is unknown. We use Demographic and Health Survey (DHS) data (n = 40,073) from 29 low- and middle-income countries to estimate the temperature-related burden of neonatal deaths between ...