Ridde, Valéry Gautier, Lara Dagenais, Christian Chabrol, Fanny Hou, Renyou Bonnet, Emmanuel David, Pierre-Marie Cloos, Patrick Duhoux, Arnaud Lucet, Jean-Christophe
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Published in
Health Research Policy and Systems
BackgroundAll prevention efforts currently being implemented for COVID-19 are aimed at reducing the burden on strained health systems and human resources. There has been little research conducted to understand how SARS-CoV-2 has affected health care systems and professionals in terms of their work. Finding effective ways to share the knowledge and ...
Levaillant, Mathieu Marcilly, Romaric Levaillant, Lucie Michel, Philippe Hamel-Broza, Jean-François Vallet, Benoît Lamer, Antoine
Introduction: Many recent studies have investigated the hospital volume-outcome relationship in surgery. In some cases, the results have prompted the centralization of surgical activity. However, the methodologies and interpretations differ markedly from one study to another. The objective of the present scoping review was to describe the various f...
Ohsfeldt, Robert Kelton, Kari Klein, Tim Belger, Mark Mc Collam, Patrick L. Spiro, Theodore Burge, Russel Ahuja, Neera
Published in
Clinical Therapeutics
Purpose The COV-BARRIER Phase 3 trial demonstrated that treatment with baricitinib, an oral selective Janus kinase 1/2 inhibitor, in addition to standard of care significantly reduced mortality over 28 days in hospitalized COVID-19 participants, with a similar safety profile to standard of care. We assessed the cost-effectiveness of baricitinib plu...
Chong, Krystle Y McDonald, Rebecca J Fan, Ming Mol, Ben W
Published in
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Evidence-based medicine tries to support clinicians through research, integrated with clinical skill and patient values. This pilot study aimed to assess appropriateness and level of evidence of current clinical practices, through evaluating availability and quality of guidelines.A prospective observational study in a large tertiary hospital networ...
Malheiro, Rui Peleteiro, Bárbara Correia, Sofia
Published in
Antimicrobial Resistance and Infection Control
Background Hospital characteristics have been recognized as potential risk factors for surgical site infection for over 20 years. However, most research has focused on patient and procedural risk factors. Understanding how structural and process variables influence infection is vital to identify targets for effective interventions and to optimize h...
Areia, Carlos Biggs, Christopher Santos, Mauro Thurley, Neal Gerry, Stephen Tarassenko, Lionel Watkinson, Peter Vollam, Sarah
Published in
Critical Care
Background Timely recognition of the deteriorating inpatient remains challenging. Wearable monitoring systems (WMS) may augment current monitoring practices. However, there are many barriers to implementation in the hospital environment, and evidence describing the clinical impact of WMS on deterioration detection and patient outcome remains unclea...
Pauwels, Ines Versporten, Ann Vermeulen, Helene Vlieghe, Erika Goossens, Herman
Published in
Antimicrobial Resistance and Infection Control
Background The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) provides a methodology to support hospitals worldwide in collecting antimicrobial use data. We aim to evaluate the impact of the Global-PPS on local antimicrobial stewardship (AMS) programmes and assess health care professionals’ educational needs...
Bailie, Christopher R. Leung, Vivian K. Orr, Elizabeth Singleton, Elizabeth Kelly, Cate Buising, Kirsty L. Cowie, Benjamin C. Kirk, Martyn D. Sullivan, Sheena G. Marshall, Caroline
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Published in
Infection, Disease & Health
Background Hospital-based contact tracing aims to limit spread of COVID-19 within healthcare facilities. In large outbreaks, this can stretch resources and workforce due to quarantine of uninfected staff. We analysed the performance of a manual contact tracing system for healthcare workers (HCW) at a multi-site healthcare facility in Melbourne, Aus...
Van Wilder, Astrid Brouwers, Jonas Cox, Bianca Bruyneel, Luk De Ridder, Dirk Claessens, Fien Eeckloo, Kristof Vanhaecht, Kris
Published in
BMC Health Services Research
Background Quality improvement (QI) initiatives such as accreditation, public reporting, inspection and pay-for-performance are increasingly being implemented globally. In Flanders, Belgium, a government policy for acute-care hospitals incorporates aforementioned initiatives. Currently, questions are raised on the sustainability of the present poli...
Andersen, Aino L. Houlind, Morten B. Nielsen, Rikke L. Jørgensen, Lillian M. Treldal, Charlotte Damgaard, Morten Bengaard, Anne Kathrine Juul-Larsen, Helle Gybel Laursen, Louise Bolvig Iversen, Esben
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Published in
Trials
Background Internationally, older patients (≥65 years) account for more than 40% of acute admissions. Older patients admitted to the emergency department (ED) are frequently malnourished and exposed to inappropriate medication prescribing, due in part to the inaccuracy of creatinine-based equations for estimated glomerular filtration rate (eGFR). T...
