Li, Xiaoya Peng, Xinxin Guo, Kangxiao Tan, Zhoujin
Published in
3 Biotech
This study aimed to explore the effect of Dendrobium officinale (DO) on the diversity of intestinal mucosal flora in high-fat diet mice and provided an experimental basis for the development and research of DO and its series products. Twenty-four mice were randomly assigned to four equal groups of six mice, namely the control (bcm) group, model (bm...
Zamani-Garmsiri, Fahimeh Hashemnia, Seyyed Mohammad Reza Shabani, Maryam Bagherieh, Molood Emamgholipour, Solaleh Meshkani, Reza
Published in
The Journal of nutritional biochemistry
Metformin (MET) and genistein (GEN) have a beneficial role in alleviating non-alcoholic fatty liver disease (NAFLD), but their combined effect on this disease has not yet been studied. The present study aimed to investigate the potential protective effects of combined MET and GEN on NAFLD in high-fat diet (HFD) fed mice. C57BL/6 male mice were fed ...
Suzuki-Kemuriyama, Noriko Abe, Akari Uno, Kiniko Ogawa, Shuji Watanabe, Atsushi Sano, Ryuhei Yuki, Megumi Miyajima, Katsuhiro Nakae, Dai
Published in
Lipids in Health and Disease
BackgroundNonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans fatty acids (TFAs) because of potential hazards to human health and the increased risk for NASH. However, the health benefits of...
Belančić, Andrej
Published in
Obesity medicine
The overall intestinal lipopolysaccharide (LPS) composition in the individuals with obesity could be shifted away from immunosilent/immunoinhibitory Bacteroidetes LPS subtypes, in favor of various proinflammatory LPS subtypes due to gut microbiome dysbiosis. What is more, high-fat diet, as well as obesity per se, enhance intestinal permeability thr...
Zhang, Yuexia Ge, Shanshan Yang, Zhenhua Li, Zhongping Gong, Xiaojuan Zhang, Quanxi Dong, Wenjuan Dong, Chuan
Published in
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Di-(2-ethylhexyl) phthalate (DEHP), which is widely used as an industrial plasticizer, may cause liver damage. Concomitantly, bad dietary habits can exacerbate the liver burden. In this study, high-fat diet (HFD)-fed rats were treated with DEHP (10, 100, or 300 mg/kg bw) for 5 weeks, and a biochemical method was adopted to detect serum lipid conten...
Zhao, Zhimeng Yao, Minmin Wei, Lan Ge, Shengjin
Published in
Nutritional neuroscience
Objectives: To investigate the effects of obesity caused by high-fat diet (HFD) on postoperative cognitive dysfunction (POCD) and expression of the Sirt1/PGC-1α/FNDC5/BDNF pathway in the hippocampus of older mice. Methods: Fifty-six 15-month-old male C57BL/6 mice were randomly divided into eight groups - ad libitum control (ALC), ad libitum surgery...
Zhang, Zheng Liu, Hao Yu, Bin Tao, Haiteng Li, Jianpeng Wu, Zhengzong Liu, Guimei Yuan, Chao Guo, Li Cui, Bo
...
Published in
Food research international (Ottawa, Ont.)
High-fat diets (HFDs) can induce health problems including gut microbiota dysbiosis and cardiac dysfunction. In this study, we modulated the gut microbiota in mice to investigate whether Lycium barbarum polysaccharide (LBP), a potential prebiotic fiber, could alleviate HFD-induced myocardial injury. Mice fed a HFD were given LBP (HFPD group) by gav...
Deshpande, Sharvari S. Nemani, Harishankar Arumugam, Gandhimathi Ravichandran, Avinash Balasinor, Nafisa H.
Published in
Clinical Epigenetics
BackgroundPaternal obesity has been associated with reduced live birth rates. It could lead to inheritance of metabolic disturbances to the offspring through epigenetic mechanisms. However, obesity is a multifactorial disorder with genetic or environmental causes. Earlier we had demonstrated differential effects of high-fat diet-induced obesity (DI...
Gawlińska, Kinga Gawliński, Dawid Korostyński, Michał Borczyk, Małgorzata Frankowska, Małgorzata Piechota, Marcin Filip, Małgorzata Przegaliński, Edmund
Published in
Developmental cognitive neuroscience
Environmental factors such as maternal diet, determine the pathologies that appear early in life and can persist in adulthood. Maternally modified diets provided through pregnancy and lactation increase the predisposition of offspring to the development of many diseases, including obesity, diabetes, and neurodevelopmental and mental disorders such ...
Konda, Prabhakar Yellanur Chennupati, Vidyasagar Dasari, Sreenivasulu Sharma, Nishesh Muthulingam, Muthukumaran Ramakrishnan, Ranjani Sade, Ankanna Jagadheeshkumar, Vigneshwari Natesan, Vijayakumar Jaiswal, Krishna Kumar
...
Published in
Journal of ethnopharmacology
The ethnopharmacological significance of the fruits of Syzygium paniculatum Gaertn (Magenta Cherry) is widely recognized in the Indian traditional medicine system to treat various disorders, such as diabetes, hyperlipidaemia, hypertension, and cardiovascular problems. This research work investigated the supplementation of the aqueous extract of S. ...