Journal of the American Society of Cytopathology
Although The Bethesda System for Reporting Cervical Cytopathology does not mandate reporting of endocervical glandular involvement (EGI) in Papanicolaou test specimens with high-grade squamous intraepithelial lesions (HSIL), several studies have suggested that EGI diagnosed on surgical specimens is associated with higher rates of residual or recurr...
Journal of virological methods
HPV-based screening provides greater protection against cervical cancer (CC) than cytology-based strategies. Currently, several molecular diagnostic assays for the detection of human papillomavirus (HPV) are available. In this study, we analyzed 5 different HPV testing and genotyping techniques (Hybrid Capture 2 [HC2; Qiagen, Hilden, Germany], Anyp...
Biomedical Research and Therapy
Objective:To study and to derive the significance of expression of p53, pRb and Ki-67 markers in various grades of cervical intraepithelial lesions and malignancy in a tertiary hospital situated in southern part of India which caters the rural and semi-urban population.Methods:A total of 120 cervical tissue samples were included. These represented ...
Journal of Racial and Ethnic Health Disparities
ObjectiveThe purpose of this study was to determine the prevalence of high-grade squamous intraepithelial lesions (HSIL) in an adolescent population diagnosed at an urban university hospital.MethodsThis study was a retrospective review of Pap smear diagnoses from January 1997 through August 2010. Patients ≤20 years were compared with records of pat...
American Journal of Obstetrics and Gynecology
Objective At present, clinical management of women referred to colposcopy but found to have