Lee, Ji Min Wei, Shu-Chen Lee, Kang-Moon Ye, Byong Duk Mao, Ren Kim, Hyun-Soo Park, Soo Jung Park, Sang Hyoung Oh, Eun Hye Im, Jong Pil
...
Published in
Gut and liver
Little is known about the clinical course of hepatitis B virus (HBV)-infected patients undergoing anti-tumor necrosis factor α (TNF-α) therapy for inflammatory bowel disease (IBD). We aimed to investigate the clinical course of HBV infection and IBD and to analyze liver dysfunction risks in patients undergoing anti-TNF-α therapy. This retrospective...
Sun, Yuan-dong Zhang, Hao Chen, Ye-qiang Wu, Chun-xue Chen, Miao-ling Xu, Hui-rong Wang, Shuo Liu, Jing-zhou Han, Jian-jun
Published in
BMC Cancer
1. High BMI combined with HBV infection has a negative impact on the PFS and OS of HCC patients treated with TACE. 2. Irrespective of TACE, the average HMGB1 in hepatitis and obesity patients was higher than that in normal individuals, which was not upregulated after TACE. 3. Patients without overweight and HBV infection had a low level of serum co...
Lv, Xiaoqin Xiang, Xia Wu, Yue Liu, Yang Xu, Ruqing Xiang, Qin Lai, Guoqi
Published in
Virology Journal
Background GATA binding protein 4 (GATA4) has been reported as a potential target of gene therapy for hepatocellular carcinoma (HCC). It is well known that the main cause of HCC is the chronic infection of hepatitis B virus (HBV). However, whether the effect of GATA4 on HBV has not yet been reported. Methods In this study, the regulation of GATA4 o...
Thongsri, Piyanoot Pewkliang, Yongyut Borwornpinyo, Suparerk Wongkajornsilp, Adisak Hongeng, Suradej Sa-ngiamsuntorn, Khanit
Published in
Scientific Reports
Hepatitis B virus (HBV) has been implicated in hepatitis and hepatocellular carcinoma. Current agents (nucleos(t)ide analogs and interferons) could only attenuate HBV infection. A combination of agents targeting different stages of viral life cycle (e.g., entry, replication, and cccDNA stability) was expected to eradicate the infection. Curcumin (C...
Afrakhteh, Hossein Joharinia, Negar Momen, Akhtar Dowran, Razieh Babaei, Abouzar Namdari, Parisa Motamedifar, Mohammad Jahromi, Bahia Namavar Sarvari, Jamal
Published in
International Journal of Reproductive Biomedicine
Background About 8-12% of couples on reproductive age suffers from infertility worldwide. Since 1993, the role of genital tract infections by microbes, including viruses that can infect the sperm, in human infertility has been proposed. Objective To investigate the frequency of hepatitis B virus (HBV), human papilloma virus (HPV), Epstein-Barr viru...
Milosevic, Ivana Russo, Edda Vujovic, Ankica Barac, Aleksandra Stevanovic, Olja Gitto, Stefano Amedei, Amedeo
Published in
World Journal of Gastroenterology
Changes in gut microbiota influence both the gut and liver, which are strictly connected by the so-called “gut–liver axis”. The gut microbiota acts as a major determinant of this relationship in the onset and clinical course of liver diseases. According to the results of several studies, gut dysbiosis is linked to viral hepatitis, mainly hepatitis ...
Demirtas, Coskun Ozer Brunetto, Maurizia Rossana
Published in
World Journal of Gastroenterology
Surveillance with abdominal ultrasound with or without alpha-fetoprotein is recommended by clinical practice guidelines for patients who are considered to be at risk of developing hepatocellular carcinoma (HCC), including those with cirrhosis, advanced fibrosis and special subgroups of chronic hepatitis B (CHB). Application of the standard surveill...
Shang, Jin Zhou, Juan Liu, Huan Ise, Rili M. Tu, You Ran, Jinqiu Bai, Lang Tang, Hong
Published in
BMC Infectious Diseases
Background Entecavir (ETV) is recommended as a first-line anti-HBV treatment. However, many chronic hepatitis B patients initiate anti-HBV treatment such as lamivudine and telbivudine with low genetic barriers in China, which leads to compensatory mutations and increases the rate of ETV resistance. The management of ETV resistance in China is an es...
Huang, Meiting Gao, Yunfei Yin, Xueru Zhang, Xuelian Hao, Yaohua Hu, Jing Liu, Zhihua
Published in
BMC Infectious Diseases
Background Postpartum alanine transaminase (ALT) flares occur frequently in chronic hepatitis B virus (HBV)-infected mothers with antepartum antiviral therapy (AVT). We aimed to characterize the T cell immunity in HBV-infected mothers experiencing postpartum ALT flares. Methods Twenty HBV-infected pregnant women who received AVT at 26–28 weeks of g...
Srisuwarn, Praopilad Sumethkul, Vasant
Published in
World Journal of Hepatology
Utilizing kidneys from donors with hepatitis B is one way to alleviate the current organ shortage situation. However, the risk of hepatitis B virus (HBV) transmission remains a challenge that undermines the chance of organs being used. This is particularly true with hepatitis B surface antigen (HBsAg) positive donors despite the comparable long-ter...
